Results 81 to 90 of about 43,976,399 (299)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Dependency graph for short text extraction and summarization

open access: yesJournal of Information and Telecommunication, 2019
A sheer amount of text generated from microblogs and social media brings huge opportunities to the text mining applications. Many techniques such as sentiment analysis and opinion mining are proven effective to deliver insights from documents.
Nigel Franciscus   +2 more
doaj   +1 more source

Text+ goes BiblioCon 2024

open access: yes
Bei der BiblioCon 2024, die unter dem Thema "offen.lokal.global." Anfang Juni in Hamburg veranstaltet wird, ist Text+ mit mehreren Beiträgen vertreten. Die BiblioCon (ehemals "Bibliothekartag") ist die zentrale Tagung des deutschen Bibliothekswesens, die
Text+ Blog-Redaktion
core   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Short Text Classification Based on Explicit and Implicit Multiscale Weighted Semantic Information

open access: yes, 2023
Considering the poor effect of short text classification due to insufficient semantic information mining in the current short text matching methods, a new short text classification method is proposed based on explicit and implicit multiscale weighting ...
Juling Zhang   +4 more
core   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

open access: yesFEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court   +3 more
wiley   +1 more source

Robust Chinese Short Text Entity Disambiguation Method Based on Feature Fusion and Contrastive Learning

open access: yesInformation
To address the limitations of existing methods of short-text entity disambiguation, specifically in terms of their insufficient feature extraction and reliance on massive training samples, we propose an entity disambiguation model called COLBERT, which ...
Qishun Mei, Xuhui Li
doaj   +1 more source

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