Results 51 to 60 of about 1,354,840 (297)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Shot-to-shot noise cancellation for parametric oscillators

Physical Review Research
Powerful approaches to squeeze the motional state of a harmonic oscillator rely on the stepwise modulation of its resonance frequency. Such protocols can be limited by forces that vary slowly between experimental runs but are constant during a single ...
Martynas Skrabulis, Martin Colombano Sosa, Nicola Carlon Zambon, Andrei Militaru, Massimiliano Rossi, Lukas Novotny, Martin Frimmer   +6 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Shot-to-shot acquisition ultrafast electron diffraction [PDF]

Structural Dynamics
We demonstrate a novel shot-to-shot acquisition method for optical pump—keV electron energy probe in ultrafast scattering experiments. We integrate a phase-locked acquisition scheme at a repetition rate of 20 kHz in a conventional ultrafast electron ...
Rémi Claude, Michele Puppin, Bruce Weaver, Paolo Usai, Thomas LaGrange, Fabrizio Carbone   +5 more
doaj   +1 more source

Sub-Poissonian Shot Noise in Graphene [PDF]

Physical Review Letters, 2006
We calculate the mode-dependent transmission probability of massless Dirac fermions through an ideal strip of graphene (length L, width W, no impurities or defects) to obtain the conductance and shot noise as a function of Fermi energy. We find that the minimum conductivity of order e2/h at the Dirac point (when the electron and hole excitations are ...
Tworzydlo, J., Trauzettel, B., Titov, M.L., Rycerz, A., Beenakker, C.W.J.   +4 more
openaire   +6 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Probing the internal energy structure of a serially coupled double quantum dot system with Rashba spin-orbit coupling through finite-frequency shot noise

AIP Advances, 2018
The finite-frequency shot noise of electron transport through a serially coupled double quantum dot system with Rashba spin-orbit coupling is studied based on an effective particle-number-resolved quantum master equation.
Hai-Bin Xue, Xu-Ping Liu, Bin Chen
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Shot noise generated by graphene p–n junctions in the quantum Hall effect regime [PDF]

, 2015
International audienceGraphene offers a unique system to investigate transport of Dirac Fermions at p–n junctions. In a magnetic field, combination of quantum Hall physics and the characteristic transport across p–n junctions leads to a fractionally ...
Hibino, H., Kumada, N., Glattli, D. C., Roulleau, P., Parmentier, F. D.   +4 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source