The impact of bias due to exponentiation in the estimation of hazard, risk, and odds ratios: an empirical investigation from 1,495,059 effect sizes from MEDLINE/PubMed abstracts. [PDF]
Košuta T +4 more
europepmc +1 more source
SiCmiR Atlas: Single‐Cell miRNA Landscape Reveals Hub‐miRNA and Network Signatures in Human Cancers
SiCmiR predicts mature miRNA activity at single‐cell resolution using only 977 landmark genes, enabling scalable reconstruction of miRNA landscapes across diverse tissues and disease contexts. The SiCmiR Atlas integrates 9.36 million cells with analytical tools for hub‐miRNA discovery, biomarker prioritization, and regulatory network interrogation ...
Xiao‐Xuan Cai +12 more
wiley +1 more source
Surface Chemistry and Particle Morphology Changes in Pine Biomass under Indirect Thermal Gradients: Implications for Feed Screw Design. [PDF]
Zeng Y +5 more
europepmc +1 more source
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang +7 more
wiley +1 more source
Macroscopic and Microscopic Performance Study of Filling-Type Large-Size Cement-Stabilized Macadam. [PDF]
Ran J +7 more
europepmc +1 more source
A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan +12 more
wiley +1 more source
James-Stein Estimator Improves Accuracy and Sample Efficiency in Human Kinematic and Metabolic Data. [PDF]
Alwan A, Srinivasan M.
europepmc +1 more source
Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu +4 more
wiley +1 more source
Transfer-learning on federated observational healthcare data for prediction models using Bayesian sparse logistic regression with informed priors. [PDF]
Li KM +4 more
europepmc +1 more source
This study develops a deep learning‐based pathomics model to predict survival outcomes in pancreatic cancer patients. The CrossFormer architecture analyzes routine H&E‐stained tissue slides, identifying key prognostic features including stromal patterns, cellular characteristics, and immune infiltration.
Qiangda Chen +22 more
wiley +1 more source

