Results 111 to 120 of about 117,953 (306)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

PROFILE OF PATIENTS WITH SHUNT BLOCKAGE IN VENTRICULOPERITONEAL SHUNTS FOR HYDROCEPHALOUS

Gomal Journal of Medical Sciences, 2015
Background: Ventriculoperitoneal shunt is the commonest treatment modality of established hydrocephalous. The objective of this study was to determine the sex and age distribution, post op year of shunt obstruction and site and causes of ...
Riaz ur Rehman, Sohail Amir, Mushtaq Khalil, Mewat Shah, Azad Bakht, Ayaz Ahmad   +5 more
doaj  

Interference of Descemet's Membrane with Aqueous Humor Drainage via an ExPRESS Mini Shunt

Case Reports in Ophthalmology, 2014
Purpose: To describe a case in which Descemet's membrane interfered with aqueous humor drainage through an ExPRESS mini shunt. This problem was successfully solved by Nd:YAG laser membranotomy.
Rikiya Tamaki, Masahiro Zako
doaj   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Model for End‐Stage Liver Disease/Pediatric End‐Stage Liver Disease exception policy and outcomes in pediatric patients with hepatopulmonary syndrome requiring liver transplantation

Liver Transplantation, EarlyView., 2022
Abstract Hepatopulmonary syndrome (HPS) is associated with increased waitlist mortality in liver transplantation (LT) candidates. Children with HPS are granted Model for End‐Stage Liver Disease (MELD)/Pediatric End‐Stage Liver Disease (PELD) exception points for waitlist prioritization in the United States based on criterion developed for adults.
Muhammad H. Raza, Yong Kwon, Pierre Kobierski, Asish C. Misra, Angelina Lim, Cameron Goldbeck, Kambiz Etesami, Rohit Kohli, Juliet Emamaullee   +8 more
wiley   +1 more source

Can ankle-brachial index be used as a predictor for carotid artery shunt application during carotid endarterectomy?

Turkish Journal of Vascular Surgery, 2021
Objectives: This study aims to investigate the possible relationship between low ankle-brachial index (ABI) and shunt requirement during carotid endarterectomy (CEA) operations.
Mehmet Akif Onalan, Didem Melis Oztaş, Ayşenur Onalan, Metin Onur Beyaz, Siraslan Bahseliyev, Zerrin Sungur, Omer Ali Sayın, Murat Uğurlucan   +7 more
doaj  

Transcatheter closure of Ventricular Septal defects in Malta : initial experience [PDF]

, 2005
Ventricular septal defects (VSD) consist of deficiencies of the wall separating the two ventricles. VSDs are the commonest congenital cardiac defects. Small VSDs rarely require intervention, however, larger defects cause ventricular volume overload with ...
Aquilina, Oscar, DeGiovanni, Joseph V., Fenech, Albert, Formosa Gouder, Mireille, Grech, Victor E., Magic, Jadran, Manche, Alexander   +6 more
core  

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt, Paola Mian, Femke Groen, Denise van den Berg‐Zuiddam, Andrea E. van der Meulen, Femke Crouwel, Nanne K. de Boer, Debbie S. Deben, Dennis R. Wong, Luc J. J. Derijks, Gerard Dijkstra, Arno R. Bourgonje, C. Janneke van der Woude, Marijn C. Visschedijk   +13 more
wiley   +1 more source

Abdominal cerebrospinal fluid pseudocysts in patients with ventriculoperitoneal shunts: 30 years of experienceFNx01

Journal of Indian Association of Pediatric Surgeons, 2007
Aim: We evaluated the treatment outcome of the patients having cerebrospinal fluid pseudocyst following ventriculo-peritoneal shunt. Materials and Methods: During the period of 1975 to 2005, 392 hydrocephalic patients underwent ventriculo-peritoneal ...
Sanal M, Laimer E, Haussler B, Hager J
doaj  

CSF inflammatory markers differ in gram-positive versus gram-negative shunt infections

Journal of Neuroinflammation, 2019
Background Cerebrospinal fluid (CSF) shunt placement is frequently complicated by bacterial infection. Shunt infection diagnosis relies on bacterial culture of CSF which can often produce false-negative results.
Gwenn L. Skar, David Synhorst, Matthew Beaver, Jessica N. Snowden   +3 more
doaj   +1 more source