Results 151 to 160 of about 117,953 (306)

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

open access: yesInterdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu   +6 more
wiley   +1 more source

Microelectromechanical system‐based devices for the diagnosis, treatment, and monitoring of ophthalmic diseases

open access: yesInterdisciplinary Medicine, EarlyView.
Due to the characteristics of miniaturization, high sensing performance, integration, and high comfort, MEMS‐based devices were employed to design sensors, imaging systems, drug delivery systems, retinal prosthesis, surgical tools, and wearable products for the ophthalmic disease diagnosis, treatment, and monitoring.
Yaling Peng   +10 more
wiley   +1 more source

Percutaneous Closure of Patent Foramen Ovale in a Patient With Incomplete Cor Triatriatum Sinister: A Case Report

open access: yesJournal of Clinical Ultrasound, EarlyView.
We present the case of a 55‐year‐old male who experienced a cryptogenic ischemic stroke, likely due to a patent foramen ovale (PFO) in the setting of an incomplete cor triatriatum sinister (CTS) and a 30 mm GORE Cardioform Septal Occluder was successfully implanted.
Anastasios Apostolos   +8 more
wiley   +1 more source

Quantification of Tricuspid Valve Regurgitation With 2D and 4D‐Flow MRI: Comparison of Different Methods in Adult Patients With Ebstein's Anomaly

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Ebstein's anomaly (EA) is a congenital heart disorder involving tricuspid valve dysplasia and right heart abnormalities resulting in severe tricuspid regurgitation (TR). Multiple techniques assess regurgitation severity, but their correlation with EA severity markers remains unclear. Purpose To compare MRI techniques for quantifying
Eric Buffle   +8 more
wiley   +1 more source

GLIM criteria for the diagnosis of malnutrition in patients with cirrhosis: A narrative review

open access: yesJournal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background This narrative review aims to describe and discuss the validity of the Global Leadership Initiative on Malnutrition (GLIM) criteria in patients with cirrhosis. Methods The literature search was performed in PubMed and EMBASE between May and August 2024 and updated in January 2025, including original studies published in English in ...
Bárbara Chaves Santos   +6 more
wiley   +1 more source

Portacaval shunt in hyperlipidemia [PDF]

open access: yes, 1974
Chase, HP   +5 more
core  

Successful propranolol therapy for infantile hepatic hemangioma with cardiac failure

open access: yesJPGN Reports, EarlyView.
Abstract Infantile hepatic hemangioma (IHH) can cause severe complications such as high‐output cardiac failure and growth faltering, requiring prompt diagnosis and intervention. In the absence of standardized treatment guidelines, propranolol has emerged as an effective and well‐tolerated therapy.
Fadhel Al Ateeqi   +4 more
wiley   +1 more source

Pre‐ and Post‐Interventional Hemodynamic Characterization of the Femoropopliteal Artery Using Vector Flow Imaging in Peripheral Arterial Occlusive Disease

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Objectives The femoropopliteal (FP) artery is the most frequently revascularized segment in peripheral artery disease (PAD), followed by the iliac segment. Wall shear stress (WSS) is a key local factor implicated in both atherosclerotic plaque formation and restenosis after angioplasty.
Jan Lukas Prüser   +5 more
wiley   +1 more source

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