Results 11 to 20 of about 13,350 (194)

Evaluating the Process of Patient Engagement: Insights from a Mixed-Methods Evaluation of a Cancer Center Patient Advisory Group. [PDF]

open access: yesHealth Expect
ABSTRACT Background Patient engagement is associated with improved care quality, better health outcomes, increased trust and satisfaction, and reduced costs. Patient engagement is recommended in cancer care. Patient advisory groups (PAGs) are a commonly used approach for engaging patients.
Kearney L   +6 more
europepmc   +2 more sources

A Phase 1 Trial of Fimepinostat in Children and Adolescents With Relapsed and Refractory Solid and CNS Tumors. [PDF]

open access: yesCancer Med
ABSTRACT Background Fimepinostat, an oral dual inhibitor of histone deacetylase (HDAC) and phosphatidylinositol‐4,5‐bisphosphate 3‐kinase (PI3K), has shown activity in preclinical models of Myc‐driven pediatric malignancies. This Phase 1 trial aimed to determine the recommended pediatric Phase 2 dose (RPP2D), describe the toxicity profile, and evaluate
Shulman DS   +13 more
europepmc   +2 more sources

Contemporary Characteristics and Outcomes of Pediatric Oncology Patients Participating in Early Phase Clinical Trials. [PDF]

open access: yesCancer Med
ABSTRACT Background Phase 1 or phase 1/2 trials are a first step in pediatric cancer drug development. Currently, there is a paucity of information regarding contemporary outcomes for pediatric patients enrolled in these trials. We describe characteristics and outcomes of patients enrolled in pediatric phase 1 clinical trials over a 9‐year period at a ...
Rami A   +8 more
europepmc   +2 more sources

Overcoming Low-Field Limitations: High-Quality Ex Vivo Soft Tissue Imaging with Compact MRI Systems. [PDF]

open access: yesCurr Protoc
Abstract High‐field magnetic resonance imaging (MRI) scanners have been the primary choice for high‐quality soft tissue imaging, but use remains limited by high costs, complex siting requirements, and infrastructure demands. In contrast, preclinical MRI scanners with a low‐field permanent magnet are increasingly being adopted in research due to their ...
Litwak A   +4 more
europepmc   +2 more sources

Deletion of NPAS4 in olfactory bulb principal neurons alters E/I balance and impairs decoding of chemically similar odour molecules. [PDF]

open access: yesJ Physiol
Abstract figure legend Conditional developmental deletion of the activity‐dependent transcription factor NPAS4 in mitral and tufted cells (ΔNPAS4M/T) impacts coding in the adult main olfactory bulb (MOB). Schematic shows exemplary inhibitory interneurons (blue) that innervate MOB projection neurons (red) that then project to the anterior olfactory ...
Wolf D   +5 more
europepmc   +2 more sources

Researching Body Perception: Toward an Integration of Quantitative and Qualitative Interdisciplinary Approaches to Address the Multiplicity of Bodily Experiences. [PDF]

open access: yesPsychophysiology
ABSTRACT Experimental psychology and cognitive neuroscience have attempted to understand the underlying functioning of one's body experience. This has resulted in standardized methods involving multisensory manipulations and physiological, behavioral, and subjective measures.
Roel Lesur M   +5 more
europepmc   +2 more sources

History of pollutant adjuvants in respiratory allergy [PDF]

open access: yesFrontiers in Allergy
Combined exposures to allergens and air pollutants emerged as a topic of concern in scientific circles by the 1980's, when it became clear that parallel increases in respiratory allergies and traffic-related air pollution had been occurring during the ...
Dennis Shusterman
doaj   +2 more sources

Colección Estéticas contemporáneas Universidad Pontificia Bolivariana

open access: yesEstudios de Filosofía, 2018
El nacimiento de la colección Estéticas contemporáneas parte de la siguiente pregunta ¿Al pensar hoy en el papel de la estética, se replantea, a su vez, la función de la filosofía? ¿Puede hablarse de una estética pragmatista?
Porfirio Cardona Restrepo   +1 more
doaj   +1 more source

Factor Analysis of the Milwaukee Inventory for Subtypes of Trichotillomania-Adult Version [PDF]

open access: yes, 2016
The Milwaukee Inventory for Subtypes of Trichotillomania-Adult Version (MIST-A; Flessner et al., 2008) measures the degree to which hair pulling in Trichotillomania (TTM) can be described as “automatic” (i.e., done without awareness and unrelated to ...
Alexander, Jennifer R.   +7 more
core   +2 more sources

SOMAESTHETICS: a plea for the acknowledgement of contingency and body in the humanistic education

open access: yesCadernos de Pesquisa, 2014
This article outlines the discussion about the importance of the principle of contingency and the role of the body for education in the humanities, according to Richard Shusterman’s neopragmatist philosophy.
Aldir Araújo Carvalho Filho
doaj   +1 more source

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