Results 161 to 170 of about 73,247 (279)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Evaluating Distributional Predictions of Search Time: Put Up or Shut Up Games (Extended Abstract)

Sean Mariasin, Andrew Coles, Erez Karpas, Wheeler Ruml, Solomon Eyal Shimony, Shahaf Shperberg   +5 more
openalex   +2 more sources

Water shut-off times for C overbore charges [PDF]

, 1962
openaire   +2 more sources

Inhba, Homer1 and Bdnf are major targets of transcriptomic dysregulation by neurodegenerative disease-associated excitotoxic NMDA receptor signaling. [PDF]

Commun Biol
Oberländer K, Pruunsild P, Koch P, Yan J, Szafranski K, Bading H.   +5 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

In-Depth Analysis of Shut-In Time Using Post-Fracturing Flowback Fluid Data—Shale of the Longmaxi Formation in the Luzhou Basin and Weiyuan Basin of China as an Example [PDF]

Lingdong Li, Xianghe Ye, Zehao Lyu, Xiaoning Zhang, Wenhua Yu, Wenhua Yu, Tianhao Huang, Xin-Xin Yu, Wenhai Yu, Wenhai Yu   +9 more
openalex   +1 more source

β₂E153 Residue at Loop B of GABA_AR Is Involved in Agonist Stabilization and Gating Properties. [PDF]

Int J Mol Sci
Michałowski MA, Brzóstowicz A, Mozrzymas JW.   +2 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Repurposing a Mature Fluvial Sandstone Reservoir in Colombia for Miscible CO₂‑EOR and Storage: Scheme Optimization and Efficiency-Retention Trade-Offs. [PDF]

ACS Omega
Abed I, Castro RH, Restrepo G, Jadhawar P.   +3 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source