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Hepatitis C Virus Vaccine Research: Time to Put Up or Shut Up [PDF]

open access: goldViruses, 2021
Unless urgently needed to prevent a pandemic, the development of a viral vaccine should follow a rigorous scientific approach. Each vaccine candidate should be designed considering the in-depth knowledge of protective immunity, followed by preclinical studies to assess immunogenicity and safety, and lastly, the evaluation of selected vaccines in human ...
Alex S. Hartlage, Amit Kapoor
openalex   +4 more sources

The tobacco industry in the time of COVID-19: time to shut it down? [PDF]

open access: closedTobacco Control, 2020
The COVID-19 pandemic which originated in China in late 2019 has spread rapidly and taken much of the world by surprise, creating a health and economic emergency likely to have significant impacts for many years. The magnitude of the threat has forced both governments and businesses to urgently elevate public health above economic principles, adapt and
Marita Hefler, Coral Gartner
openalex   +6 more sources

Simulation of reasonable shut-in time for shale oil after volume fracturing [PDF]

open access: yesYouqicang pingjia yu kaifa
To address issues such as the significant variance in shut-in effects between wells and the unclear effectiveness and timeliness of shut-ins during fracturing in shale formations, a numerical model integrating fracturing, shut-in, and production ...
LIAO Kai, ZHANG Shicheng, XIE Bobo
doaj   +4 more sources

The effect of the displacement pressure on migration of fluid during the imbibition for tight oil reservoir [PDF]

open access: yesScientific Reports
In recent years, tight oil has emerged as a significant and complex topic in the fields of oil exploration and development. Following hydraulic fracturing, wells are typically shut-in for a designated period to facilitate water uptake into shale ...
Yubin Yang   +10 more
doaj   +2 more sources

Effect of shut-in time on gas flow rate in hydraulic fractured shale reservoirs [PDF]

open access: bronzeJournal of Natural Gas Science and Engineering, 2016
Abstract Some shale gas and oil wells undergo month-long shut-in times after multi-stage hydraulic fracturing well stimulation. Field data indicate that in some wells, such shut-in episodes surprisingly increase the gas and oil flow rate. In this paper, we report a numerical simulation study that supports such observations and provides a potentially ...
Perapon Fakcharoenphol   +3 more
openalex   +3 more sources

Reusable potential-prediction of long-term shut-in oil wells

open access: yesPetroleum Exploration and Development, 2008
Comprehensive reusable potential prediction models and relevant principles are established in order to reuse the potential of long time shut-in oil wells, which have been shut-in during the high water-cut stage of an oil field, considering economic ...
Li-jun WANG   +4 more
doaj   +3 more sources

Slowness and Time Expansion in Long Takes: 2001: A Spacey Odyssey, Barry Lyndon, and Eyes Wide Shut

open access: greenCinergie, 2017
Pramaggiore claimed that Barry Lyndon is slow, similarly Ciment suggested that 2001: A Space Odyssey and Eyes Wide Shut are slow films, too. Moving from the debate on slowness, especially from Jaffe’s discussion, from the data collected in Cinemetrics ...
Elisa Pezzotta
doaj   +2 more sources

Real-Time Prediction of Shut-in Production From Hurricanes in the Gulf of Mexico

open access: greenSPE Annual Technical Conference and Exhibition, 2006
Abstract Accurate prediction of damage to petroleum production infrastructure from hurricane winds, waves, and storm surges has numerous applications to facility design, production planning, and the financial markets, among others.
Charles C. Watson, Michael E. Johnson
openalex   +3 more sources

Time to shut down the acute care conveyor belt? [PDF]

open access: bronzeMedical Journal of Australia, 2015
Kenneth Hillman   +2 more
openalex   +3 more sources

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