The Impact of Sport Activity Shut down during the COVID-19 Pandemic on Children, Adolescents, and Young Adults: Was It Worthwhile? [PDF]
Int J Environ Res Public Health, 2022 Raimondi S +11 more
europepmc +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
PENENTUAN SHUT DOWN PRICE PADA PRODUK BARANG INDUSTRI
, 2005 Dalam bidang produksi suatu barang industri akan selalu dirancang untuk dapat menentukan shut down price atau harga yang paling minimal dari keseluruhan produksi barang tersebut dengan maksud tidak akan mengalami kerugian yang besar dan berlarut ...
Kakiay, Thomas J.
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Profit sharing regulation and repeated bargaining with a shut-down option
L20, D92, Profit, Sharing, Bargaining, Regulation, Shut-down, Option,
Gianpaolo Rossini, Michele Moretto
core +1 more source
Emergencies do not shut down during a pandemic: COVID pandemic impact on Acute Care Surgery volume and mortality at a level I trauma center. [PDF]
Am J Surg, 2022 Ross SW +10 more
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Downtown Corpus Christi Shut Down "BUS STOP CLOSED" sign and street on April 17, 2020 (Photograph)
, 2020 Downtown Corpus Christi Shut Down "BUS STOP CLOSED" sign and empty downtown street on April 17, 2020 (Photograph)Downtown Corpus Christi Shut Down "BUS STOP CLOSED" sign and empty downtown street on April 17, 2020 ...
Carpenter,Cole, Bryant, Katarina
core