Results 31 to 40 of about 1,277 (217)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Insights into Carbon-Based Aerogels Toward High-Performance Lithium–Sulfur Batteries: A Review of Strategies for Sulfur Incorporation Within Carbon Aerogel Frameworks

Gels
Lithium–sulfur batteries (LSBs), possessing excellent theoretical capacities, advanced theoretical energy densities, low cost, and nontoxicity, are one of the most promising energy storage battery systems.
Yue Gao, Dun Liu, Yi Zhao, Dongdi Yang, Lugang Zhang, Fei Sun, Xiaoxiao Wang   +6 more
doaj   +1 more source

Effects of chlordiazepoxide on the acquisition of shuttle avoidance in the rabbit [PDF]

Psychonomic Science, 1970
Rabbits injected with various dosages of chlordiazepoxide showed a decrement in the acquisition of a two-way shuttle-avoidance response. It is suggested that these results are not consistent with the notion that chlordiazepoxide reduces fear.
Drake C. Chisholm, John W. Moore
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Multi‐Functional Effects of CuS as Modifier to Fabricate Efficient Interlayer for Li‐S Batteries

Advanced Science, 2022
The shuttle effect of lithium polysulfides in lithium‐sulfur batteries (LSBs) has a detrimental impact on their electrochemical performance. To effectively mitigate the shuttle effect, in this study, the coral‐like CuS is introduced to modify the carbon ...
Mengzi Geng, Hangqi Yang, Chaoqun Shang
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Energy-Saving Synthesis of Functional CoS2/rGO Interlayer With Enhanced Conversion Kinetics for High-Performance Lithium-Sulfur Batteries

Frontiers in Chemistry, 2022
Lithium sulfur (Li-S) battery has exhibited great application potential in next-generation high-density secondary battery systems due to their excellent energy density and high specific capacity.
Junan Feng, Yahui Li, Jinshi Yuan, Yuling Zhao, Jianmin Zhang, Fengyun Wang, Jie Tang, Jianjun Song   +7 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Effective Polysulfide Adsorption by Double Side Coated Separator in Lithium-Sulfur Batteries

International Journal of Electrochemical Science, 2018
Lithium-sulfur batteries have attracted much attention because of their high specific capacity and energy density. However, the commercialization of lithium-sulfur batteries is limited by low utilization of active materials and excessive capacity decay ...
Yulin Liu, Jing Li, Min Zeng, Xun Xu, Jianna Deng, Jianqiang Guo, Dan Zhao, Jianzhao Yang, Hongru Wang   +8 more
doaj   +1 more source