Results 71 to 80 of about 5,911 (268)

Application of Tire Pyrolysis Oil as an Alternative Fuel for Internal Combustion Engines—A Literature Review

open access: yesJournal of Combustion
Tire pyrolysis oil (TPO) has been recently used as an alternative to conventional fuels for internal combustion (IC) engines in order to satisfy some environmental and economic concerns. The main focus of this review is to shed light on the importance of
Keji Qi, Xuehui Gan
doaj   +1 more source

A Two-Zone Combustion Model for Knocking Prediction of Marine Natural Gas SI Engines

open access: yesEnergies, 2018
The further thermal efficiency improvement of marine natural gas engine is constrained by a knocking phenomenon that commonly occurs in gas-fueled spark-ignited engines. It plays an important role to investigate how the knocking occurs and how to predict
La Xiang, Enzhe Song, Yu Ding
doaj   +1 more source

Acetone-Gasoline Blend as an Alternative Fuel in SI Engines: A Novel Comparison of Performance, Emission, and Lube Oil Degradation. [PDF]

open access: yesACS Omega, 2023
Usman M   +8 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Adaptive Fuzzy Sliding Mode Observer for Cylinder Mass Flow Estimation in SI Engines

open access: yesIEEE Access, 2018
In this paper, a novel algorithm for the cylinder mass flow estimation in four-stroke spark ignition (SI) gasoline engines is developed to improve the estimation precision under transient conditions.
Changhui Wang, Mei Liang, Chun-Na Li
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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