Results 211 to 220 of about 113,461 (351)

Sialic Acid and Colchicine Functionalized Silica Nanoparticles: A Novel Approach to Leishmanicidal Selective Treatments. [PDF]

Biomedicines
Galue-Parra AJ, Jimenez-Falcao S, Arribas-Yuste E, Marin C, Mendez-Arriaga JM.   +4 more
europepmc   +1 more source

Diabetes and Obesity Modify the Effect of Alcohol Consumption on Carbohydrate‐Deficient Transferrin

Endocrinology, Diabetes &Metabolism, Volume 8, Issue 6, November 2025.
There is an interaction between alcohol consumption and factors associated with insulin resistance in relation to transferrin sialylation. The sensitivity of carbohydrate‐deficient transferrin for detecting heavy alcohol consumption might be limited in patients with obesity or diabetes.
Tomás González‐Vidal, Óscar Lado‐Baleato, Fátima de la Osa, Manuela Alonso‐Sampedro, Carmen Fernández‐Merino, Juan Sánchez‐Castro, Francisco Gude, Arturo González‐Quintela   +7 more
wiley   +1 more source

Studies on the Stability of Simple Derivatives of Sialic Acid

, 1964
John D. Karkas, Erwin Chargaff
openalex   +1 more source

The acid and enzymic hydrolysis of O-acetylated sialic acid residues from rabbit Tamm–Horsfall glycoprotein [PDF]

, 1972
A. Neuberger, W A Ratcliffe
openalex   +1 more source

Tumor desialylation surpasses anti‐PD‐L1 checkpoint therapy in restoring anti‐tumor immunity in a murine model for colorectal cancer

International Journal of Cancer, Volume 157, Issue 9, Page 1948-1962, 1 November 2025.
What's new? Our research highlights how tumor sialylation affects tumor growth and reshapes the immune tumor microenvironment in colorectal cancer. We demonstrate for the first time that complete removal of sialic acids from colorectal tumor cells elicits a robust anti‐tumor immune response, but does not enhance anti‐PD‐L1 blockade efficacy.
Irene van der Haar Àvila, Tao Zhang, Victor Lorrain, Eelco Keuning, Laraib Amir Ali, Cora Chadick, Sara García‐García, Louis Boon, Noortje de Haan, Juan J. García‐Vallejo, Yvette van Kooyk, Sandra J. van Vliet   +11 more
wiley   +1 more source

VARIATIONS IN THE SIALIC ACID CONCENTRATION OF GLOMERULAR BASEMENT MEMBRANE PREPARATIONS OBTAINED BY ULTRASONIC TREATMENT [PDF]

, 1970
Steven C. Mohos, L Skoza
openalex   +1 more source

Trial Readiness: Understanding the Natural History of Rare Diseases

Journal of Inherited Metabolic Disease, Volume 48, Issue 6, November 2025.
ABSTRACT Inherited metabolic diseases (IMD) represent the largest and still growing group of treatable genetic disorders and are increasingly amenable to targeted interventions that achieve varying degrees of prognostic improvement. Innovative therapies are on the horizon and offer promising opportunities for disease‐changing treatment for a variety of
Thomas Opladen, Ulrike Mütze, Florian Gleich, Sven F. Garbade, Oya Kuseyri Hübschmann, Matthias Zielonka, Stefan Kölker   +6 more
wiley   +1 more source

A sialic acid-binding protein in Toxoplasma gondii contains a conserved globular domain in apicomplexan parasites. [PDF]

Parasit Vectors
Sang X, Liu Y, Zhang Y, Chen R, Feng Y, Jiang N, Chen Q.   +6 more
europepmc   +1 more source

Studies on Sialic Acid (Neuraminic Acid) in Cerebrospinal Fluid

, 1962
Akira Mukai, Tatsunori Ejima
openalex   +2 more sources

Quantitative analysis of inhibitor‐induced assembly disruption in human UDP‐GlcNAc 2‐epimerase using mass photometry

Protein Science, Volume 34, Issue 11, November 2025.
Abstract Uridine diphosphate N‐acetylglucosamine (UDP‐GlcNAc) 2‐epimerase (GNE)/N‐acetylmannosamine kinase is the rate‐limiting enzyme in sialic acid biosynthesis and a promising therapeutic target. We applied mass photometry (MP) to investigate GNE oligomerization and its modulation by three small‐molecule inhibitors (C5, C13, and C15).
Nico Boback, Jacob Gorenflos López, Christian P. R. Hackenberger, Santiago Di Lella, Daniel C. Lauster   +4 more
wiley   +1 more source