Results 211 to 220 of about 2,579,458 (259)

Sialic acid identity modulates host tropism of sialoglycan-binding viridans group streptococci. [PDF]

open access: yesJ Biol Chem
Morrison KM   +9 more
europepmc   +1 more source

Sialic Acid Mimetics to Target the Sialic Acid–Siglec Axis [PDF]

open access: yesTrends in Biochemical Sciences, 2016
Sialic acid sugars are vital regulators of the immune system through binding to immunosuppressive sialic acid-binding immunoglobulin-like lectin (Siglec) receptors on immune cells. Aberrant sialic acid-Siglec interactions are associated with an increasing number of pathologies including infection, autoimmunity, and cancer.
Christian Büll   +2 more
exaly   +5 more sources
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Turnover of Free Sialic Acid, CMP-Sialic Acid, and Bound Sialic Acid In Rat Brain

Journal of Neurochemistry, 1981
Abstract: Adult male rats were injected intraventricularly with N‐[3H]acetylmannosamine. After different time intervals the rats were killed and free sialic acid, CMP‐sialic acid, lipid‐ and protein‐bound sialic acid were isolated from brain and the specific radioactivities determined. Maximal specific radioactivity was reached after approximately 4 h
W Ferwerda
exaly   +3 more sources

Sialic Acids in Neurology

2019
Sialic acid (Sia) is involved in many biological activities and commonly occurs as a monosialyl residue at the nonreducing terminal end of glycoconjugates. The loss of activity of UDP-GlcNAc2-epimerase/ManNAc kinase, which is a key enzyme in Sia biosynthesis, is lethal to the embryo, which clearly indicates the importance of Sia in embryogenesis ...
Chihiro, Sato, Ken, Kitajima
openaire   +2 more sources

The acidities of ascorbic and sialic acids

Journal of Chemical Education, 1970
This note concerning the pKa's of ascorbic and sialic acids id presented since the compounds are of general interest to organic chemists and carbohydrate chemists as well as biochemists.
openaire   +2 more sources

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