Results 111 to 120 of about 88,767 (266)

Childbearing patterns for Swedish mothers of twins, 1961-1999 [PDF]

open access: yes
The Nordic population registers provide a unique possibility to study the demographic behavior of very small population groups and rare events. In this paper, we study the childbearing behavior of Swedish mothers of twins between 1961 and 1999, inclusive.
Margit Strandberg, Jan M. Hoem
core  

Expert Perspective: Toward Treat‐to‐Target Management in Adult Idiopathic Inflammatory Myopathies

open access: yesArthritis &Rheumatology, Accepted Article.
Treat‐to‐target (T2T) has transformed the management of several rheumatic diseases through predefined therapeutic goals, structured disease assessment, and timely treatment adjustment. Despite major advances in the understanding and treatment of idiopathic inflammatory myopathies (IIM), a formal T2T framework for adult IIM has not yet been established.
Shiri Keret   +2 more
wiley   +1 more source

The occurrence and development of' Siamese twins' and other abnormalities in Oreochromis mossambicus (Pisces, Cichlidae). [PDF]

open access: yes, 1993
Specimens from a clutch of Oreochromis mossambicus (Pisces, Cichlidae) exhibited a number of abnormalities such as enlarged pericardia, thin tube-like hearts, large depressions in the yolksac, spinal deformities and twinning.
Bruton, Michael N, Holden, Kathleen K
core  

Dual Effects of β‐TrCP2 Deletion in Bone Homeostasis: Suppression of Osteoclastogenesis and Enhancement of Osteoblast Activity

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives To elucidate role of beta‐transducin repeat‐containing protein 2 (β‐TrCP2) in bone homeostasis for its potential as a therapeutic target for osteoporosis. Methods The role of β‐TrCP2 in bone phenotypes was investigated using systemic β‐TrCP1KO and β‐TrCP2KO mice, along with myeloid‐specific conditional β‐TrCP2KO (β‐TrCP2ΔM) mice.
Woo Jung Kim   +14 more
wiley   +1 more source

An Arthroscopic Technique for Hybrid Double‐Row Repair Using a Cancellous Screw and Washer for Enhanced Lateral‐Row Fixation in Osteoporotic Massive Rotator Cuff Tears With Long‐Head Biceps Augmentation

open access: yesArthroscopy Techniques, EarlyView.
Abstract Massive rotator cuff tears in osteoporotic bone often fail because of many factors, including poor anchor fixation. We present an arthroscopic hybrid double‐row repair technique using a unicortical cancellous screw and washer for lateral‐row fixation, combined with biceps superior capsular reconstruction.
Pakorn Chawanpaiboon   +4 more
wiley   +1 more source

A Rare Case of Conjoined Twins. [PDF]

open access: yesCureus, 2023
Shaikh S   +4 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić   +8 more
wiley   +1 more source

HLA‐B*15:21 carrier status is a susceptibility factor of carbamazepine‐induced nonimmediate cutaneous adverse reactions in HLA‐B*15:02‐negative patients: A retrospective cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
After HLA‐B*15:02 screening, the residual risk of carbamazepine‐induced nonimmediate cutaneous adverse reactions is 0.059. Among these HLA‐B*15:02‐negative cases, HLA‐B*15:11 and HLA‐B*15:21 carrier status significantly increases the risk of carbamazepine‐induced nonimmediate cADR.
Warit Ruanglertboon   +11 more
wiley   +1 more source

Efficient Tax Policy Ranks Education Higher Than Saving [PDF]

open access: yes
Assuming a two-period model with endogenous choices of labour, education, and saving, it is shown to be second-best efficient not to distort the choice of education. In general this implies distorting the saving decision.
Richter, Wolfram F.
core  

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