Solution structures of two homologous venom peptides from Sicarius dolichocephalus. [PDF]
PLoS ONE, 2013 We present solution-state NMR structures for two putative venom peptides from Sicarius dolichocephalus. These peptides were identified from cDNA libraries created from venom gland mRNA and then recombinantly expressed.
Nikolaus M Loening +3 more
doaj +7 more sources
Sphingomyelinase D Activity in Sicarius tropicus Venom: Toxic Potential and Clues to the Evolution of SMases D in the Sicariidae Family [PDF]
Toxins, 2021 The spider family Sicariidae includes three genera, Hexophthalma, Sicarius and Loxosceles. The three genera share a common characteristic in their venoms: the presence of Sphingomyelinases D (SMase D).
Priscila Hess Lopes +4 more
doaj +5 more sources
Toxicological Characterization and Phospholipase D Activity of the Venom of the Spider Sicarius thomisoides [PDF]
Toxins, 2020 Envenomation by Loxosceles spiders (Sicariidae family) has been thoroughly documented. However, little is known about the potential toxicity of members from the Sicarius genus.
Tomás Arán-Sekul +7 more
doaj +5 more sources
Venom of the Brazilian spider Sicarius ornatus (Araneae, Sicariidae) contains active sphingomyelinase D: potential for toxicity after envenomation. [PDF]
PLoS Neglected Tropical Diseases, 2013 BACKGROUND:The spider family Sicariidae includes two genera, Sicarius and Loxosceles. Bites by Sicarius are uncommon in humans and, in Brazil, a single report is known of a 17-year old man bitten by a Sicarius species that developed a necrotic lesion ...
Priscila Hess Lopes +5 more
doaj +4 more sources
Proteome Analysis of the Six-Eyed Sand-Spider Sicarius thomisoides Venom [PDF]
ToxinsSpiders of the Sicarius genera (Araneae: Sicariidae) are commonly known as six-eyed sand spiders. Of the species described in Latin America, the species S.
Tomás Arán-Sekul +5 more
doaj +3 more sources
Heterophilic antibodies in sera from individuals without loxoscelism cross-react with phospholipase D from the venom of Loxosceles and Sicarius spiders [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2018 Background Loxoscelism is a severe human envenomation caused by Loxosceles spider venom. To the best of our knowledge, no study has evaluated the presence of antibodies against Loxosceles venom in loxoscelism patients without treatment with antivenom ...
Tomás Arán-Sekul +8 more
doaj +4 more sources
A Web of Coagulotoxicity: Failure of Antivenom to Neutralize the Destructive (Non-Clotting) Fibrinogenolytic Activity of Loxosceles and Sicarius Spider Venoms [PDF]
Toxins, 2020 Envenomations are complex medical emergencies that can have a range of symptoms and sequelae. The only specific, scientifically-validated treatment for envenomation is antivenom administration, which is designed to alleviate venom effects.
Dwin Grashof +7 more
doaj +2 more sources
Specificity of Loxosceles α clade phospholipase D enzymes for choline-containing lipids: Role of a conserved aromatic cage. [PDF]
PLoS Computational Biology, 2022 Spider venom GDPD-like phospholipases D (SicTox) have been identified to be one of the major toxins in recluse spider venom. They are divided into two major clades: the α clade and the β clade.
Emmanuel E Moutoussamy +7 more
doaj +2 more sources
Hold the Chemo! Leukostasis, a Presentation of Brown Recluse Spider Bite: A Case Report [PDF]
Journal of Investigative Medicine High Impact Case Reports, 2021 Brown recluse spiders, also known as Loxosceles reclusa, are endemic to the Southwest and Central Midwestern United States. A bite from this spider can cause a range of clinical manifestations, anywhere from a painless papular lesion to life-threatening ...
Ahmad Hallak MD +5 more
doaj +2 more sources
The sicariid spiders in the state of Bahia, Brazil (Arachnida: Araneae) [PDF]
PeerJBackground Sicariidae is a small family of cryptic and recluse spiders, with 178 species grouped into three genera: Hexophtalma, Loxosceles and Sicarius.
Júlia Andrade-de-Sá +3 more
doaj +3 more sources