A Functional Assay for Sick Sinus Syndrome Genetic Variants
Background/Aims: Congenital Sick Sinus Syndrome (SSS) is a disorder associated with sudden cardiac death due to severe bradycardia and prolonged pauses.
Chuanchau J. Jou+12 more
doaj +2 more sources
A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene
Sick sinus syndrome (SSS) is a group of heart rhythm disorders caused by malfunction of the sinus node, the heart’s primary pacemaker. Partially owing to its aging-associated phenotypic manifestation and low expressivity, molecular mechanisms of SSS ...
Yonghe Ding+14 more
semanticscholar +1 more source
Neuroimaging for differential diagnosis of transient neurological attacks
Abstract Background Rapid yet comprehensive neuroimaging protocols are required for patients with suspected acute stroke. However, stroke mimics can account for approximately one in five clinically diagnosed acute ischemic strokes and the rate of thrombolyzed mimics can be as high as 17%.
Ying Wang, Hao Zha
wiley +1 more source
Older patients with COVID‐19 and neuropsychiatric conditions: A study of risk factors for mortality
Abstract Background Little is known about risk factors for mortality in older patients with COVID‐19 and neuropsychiatric conditions. Methods We conducted a multicentric retrospective observational study at Assistance Publique‐Hôpitaux de Paris. We selected inpatients aged 70 years or older, with COVID‐19 and preexisting neuropsychiatric comorbidities
Vi‐Huong Nguyen‐Michel+23 more
wiley +1 more source
Background This case report presents a patient diagnosed with sick sinus syndrome who was successfully treated with permanent His-bundle pacing (PHBP). Case presentation A 36-year-old man was transferred to our hospital due to recurrent syncope.
Zai-Qiang Zhang, Jia-Wang Ding
doaj +1 more source
Transforming Growth Factor-β1 T869C Gene Polymorphism Is Associated with Acquired Sick Sinus Syndrome via Linking a Higher Serum Protein Level. [PDF]
Familial sick sinus syndrome is associated with gene mutations and dysfunction of ion channels. In contrast, degenerative fibrosis of the sinus node tissue plays an important role in the pathogenesis of acquired sick sinus syndrome.
Jan-Yow Chen+5 more
doaj +1 more source
Generating Visual Information for Motion Sickness Reduction Using a Computational Model Based on SVC Theory [PDF]
With the advancements in automated driving, there is concern that motion sickness will increase as non-driving-related tasks increase. Therefore, techniques to reduce motion sickness have drawn much attention. Research studies have attempted to estimate motion sickness using computational models for controlling it. Among them, a computational model for
arxiv +1 more source
Abstract Background The proadaptive effects of glucagon‐like peptide‐2 (GLP‐2) include stimulation of intestinal mucosal growth as well as intestinal blood flow and angiogenesis. We have recently reported that daily subcutaneous injections of glepaglutide, a long‐acting GLP‐2 analog, improved intestinal absorptive function in patients with short bowel ...
Rahim M. Naimi+9 more
wiley +1 more source
The sinoatrial node (SAN), the primary pacemaker of the heart, consists of a heterogeneous population of specialized cardiac myocytes that can spontaneously produce action potentials, generating the rhythm of the heart and coordinating heart contractions.
D. Lang, A. Glukhov
semanticscholar +1 more source
WisdomNet: Prognosis of COVID-19 with Slender Prospect of False Negative Cases and Vaticinating the Probability of Maturation to ARDS using Posteroanterior Chest X-Rays [PDF]
Coronavirus is a large virus family consisting of diverse viruses, some of which disseminate among mammals and others cause sickness among humans. COVID-19 is highly contagious and is rapidly spreading, rendering its early diagnosis of preeminent status.
arxiv +1 more source