Results 111 to 120 of about 5,070,713 (217)

Metabolic stimulation improves bioenergetics and haematologic indices of circulating erythrocytes from sickle cell mice

The Journal of Physiology, EarlyView.
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida, Meghann L. Smith, Sayuri Kamimura, Sebastian Vogel, Zenaide M. N. Quezado   +4 more
wiley   +1 more source

Venous Oxygenation Measurements in the Upper Arm: Reproducibility and Sensitivity to a Physical Challenge

Magnetic Resonance in Medicine, Volume 96, Issue 6, Page 2894-2906, December 2026.
ABSTRACT Purpose The feasibility and reproducibility of adapting the T2‐Relaxation‐Under‐Spin‐Tagging (TRUST) MRI sequence for noninvasive measurement of venous oxygenation in the upper arm were investigated, aiming to enable future in vivo validation of T2b‐oxygenation calibration curves in sickle cell disease (SCD).
J. Diogo Fernandes, Koen P. A. Baas, Matthan W. A. Caan, Bart J. Biemond, John C. Wood, Aart J. Nederveen   +5 more
wiley   +1 more source

Identifying (Mis)conceptions About Genetic Information: Perspectives of Current and Future Teachers and Psychologists

Mind, Brain, and Education, Volume 20, Issue 4, November 2026.
ABSTRACT Rapid advances in genomics may soon enable low‐cost predictions of children's academic potential. To ensure this knowledge is used responsibly in educational settings, stakeholders require sound genetic literacy. This study assessed genetic knowledge, perceived heritability, and genetic attitudes in preservice teachers (n = 236; 83% female ...
Belinda Wauge, Sally A. Larsen, Brian Byrne   +2 more
wiley   +1 more source

Improvement of Sickle Cell Disease Care Mitigates the Healthcare Utilization Induced by Increased Prevalence: Experience of a Tertiary Pediatric Center

Pediatric Blood &Cancer, Volume 73, Issue 10, October 2026.
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna, Alexia Muresan, Estelle Lecluze, Karine Leduc, Nathalie Fournier, Maria Tamer, Jean‐François Delisle, Jeremi Charbonneau, Annie Viau, Jessica Darilus, Marie‐Joëlle Doré‐Bergeron, Valérie Arsenault, Evelyne Doyon‐Trottier, Stéphanie Forte, Nancy Robitaille, Yves Pastore, Thomas Pincez   +16 more
wiley   +1 more source

Secretory Phospholipase A2 in Patients With Sickle Cell Disease Hospitalized for Vaso‐Occlusive Pain Episodes

Pediatric Blood &Cancer, Volume 73, Issue 10, October 2026.
ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman, Maria Yasmine, Dunia Hatabah, Noor Alzraikat, Frank Harris, Lou Ann Brown, Satheesh Chonat, Nitya Bakshi, Chris A. Rees, Carlton Dampier, Claudia R. Morris   +10 more
wiley   +1 more source

The Bloodline newsletter : Sickle Cell Data Collection (SCDC) Program quarterly newsletter ; March 2023

Mission: To improve quality of life, life expectancy, and health among people living with sickle cell disease (SCD)

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Current advances in 2025: A critical review of selected topics by the Association for the Advancement of Blood and Biotherapies (AABB) Clinical Transfusion Medicine Committee

Transfusion, EarlyView.
Nabiha H. Saifee, Jennifer Andrews, Mary Berg, Stella T. Chou, Mischa Covington, Elizabeth P. Crowe, Ruchika Goel, Juliana A. Guarente, Tina Ipe, Jeremy W. Jacobs, Jessica Jacobson, Cyril Jacquot, Jenna Khan, Thane A. Kubik, Theodros Mamo, Michael F. Murphy, Kerry O'Brien, Monica B. Pagano, Anil K. Panigrahi, Jacqueline N. Poston, Scott E. Potter, Simon J. Stanworth, Moritz Stolla, Alyssa Ziman, Ryan A. Metcalf   +24 more
wiley   +1 more source

Peripartum Anesthetic Management of a Patient With Sickle Cell Disease and Preeclampsia

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Peripartum care for patients with sickle cell disease and preeclampsia requires coordinated multidisciplinary management. Key strategies include multimodal analgesia, individualized transfusion protocols, and vigilant maternal‐fetal monitoring.
Madeline Dow, Aariya Srinivasan, Sabry Ayad   +2 more
wiley   +1 more source

The Bloodline newsletter : Sickle Cell Data Collection (SCDC) Program quarterly newsletter ; July 2023

Mission: To improve quality of life, life expectancy, and health among people living with sickle cell disease (SCD)

core  

Pharmacotherapy of sickle cell anemia

, 2018
The pharmacology of sickle cell anaemia entails the study and of the cellular basis of most of the drugs used to manage this condition.Its pharmacodynamic and pharmacokinetics properties and the future treatment of sickle cell diseaseLBáltalános ...
Palomeras, Yemisi
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