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Sickle-Cell Anemia

Issues in Comprehensive Pediatric Nursing, 1980
Sickle-cell anemia is a genetic disorder characterized by abnormal hemoglobin. One out of every 500 black children in the United States is affected by this disease. Eight to ten percent of the black population has the sickle-cell trait. While other hemoglobinopathies have been identified that also produce erythrocyte sickling and destruction, the ...
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Sickle Cell Anemia

Postgraduate Medicine, 1952
For general practitioners, as well as specialists, this department offers the latest, proved methods of treatment of conditions encountered in an average practice. It is not, of course, intended to present these discussions as the only acceptable therapeutic procedures to be used, but rather to offer simple regimens and recommendations based on the ...
G W, JAMES, W B, PORTER
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NEONATAL SICKLE CELL ANEMIA

Journal of the American Medical Association, 1950
The purpose of this report is to emphasize the possibility of the occasional early onset of sickle cell anemia and to consider it in the differential diagnosis of jaundice during the neonatal period in the Negro. Sickle cell anemia 1 is a hereditary and congenital disease of the hemopoietic system occurring almost entirely in members of the Negro race.
C A, FRAZIER, C E, RICE
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Atypical Sickle Cell Anemia

JAMA: The Journal of the American Medical Association, 1963
Four patients presenting unusual manifestations of sickle cell anemia were studied. Clinical variants were age, habitus, and pregnancy. In some cases, these features were so atypical as to suggest disease entities other than sickle cell anemia and obscure the diagnosis.
R C, GAUSE   +3 more
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Sickle Cell Anemia

American Journal of Diseases of Children, 1923
J. B. Herrick, 1 in 1910, reported a peculiar dyscrasia characterized by severe anemia, with the occurrence in the blood of elongated and sickle-shaped erythrocytes. Three instances of this condition have since been described, one by R. E. Washburn; 2 one by Cook and Myer, 3 and one by V. R. Mason. 4 Emmel 5 further studied the blood of Cook and Myer's
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Sickle cell anemia and pregnancy

American Journal of Obstetrics and Gynecology, 1949
Abstract The present study is a review of eleven cases of sickle cell anemia associated with pregnancy observed on the Obstetrical Service of the Johns Hopkins Hospital over a 20-year period (1927–1947). No deaths occurred in these eleven mothers during the period of the pregnancy or puerperium.
G W, ANDERSON, T, BUSBY
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Sickle Cell Anemia

Annals of Internal Medicine, 1978
Excerpt To the editor: The "natural history" of sickle cell anemia in Saudi Arabs (Ann Intern Med88:1-6, 1978) is certainly different from the disease as we see it in the United States but not as d...
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Sickle Cell Anemia

2010
Sickle cell anemia (SCA or SS homozygous sickle cell disease) is an inherited blood disorder caused by single nucleotide substitution in the β-globin gene that renders their hemoglobin (HbS) much less soluble than normal hemoglobin (HbA) when deoxygenated. The polymerization of HbS upon deoxygenation is the basic pathophysiologic event leading
Connes Philippe   +3 more
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