Results 141 to 150 of about 21,712,270 (345)

Brief report of efficacy and side effect profile of crossing over to modified-release capsules of methylphenidate in ADHD patients receiving other treatments: case series

Psychiatry and Clinical Psychopharmacology, 2017
OBJECTIVES: Stimulants are recommended as the first-line pharmacotherapy in attention deficit/hyperactivity disorder (ADHD). Methylphenidate (MPH) is the most used stimulant. Medikinet Retard has modified-release capsules of MPH (MRC-MPH).
Burcu Özbaran, Sezen Köse, Fevzi Tuna Ocakoğlu, Hakan Kayış, Ayşegül Satar, Uğur Tekin   +5 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Subprime side effects in the federal funds market [PDF]

Mortgage loans ; Federal funds market (United States)
Daniel L. Thornton
core  

Importance of chirality and reduced flexibility of protein side chains: A study with square and tetrahedral lattice models

, 2004
In simple models side chains are often represented implicitly (e.g., by spin-states) or simplified as one atom. We study side chain effects using square lattice and tetrahedral lattice models, with explicitly side chains of two atoms.
Bagci, Black, Brady, Bromberg, Chan, Cole, Creamer, Creamer, Cronin, Dill, Dima, Doig, Dukor, Dunbrack, Dunbrack, Dunbrack, Hill, Jie Liang, Jinfeng Zhang, Kirshenbaum, Klimov, Kussell, Kussell, Lau, Liang, Liang, Liu, Lovell, Micheletti, Miranker, Mitchell, Park, Pickett, Richards, Richards, Rong Chen, Schafer, Shakhnovich, Tekaia, Wynn, Xia, Yu, Yu Chen, Zhang   +43 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Side Effects of Campaign Finance Reform [PDF]

Since campaign finance reform is usually motivated by the concern that existing legislation can not effectively prevent campaign contributions to “buy favors”, this paper assumes that contributions influence political decisions.
Matthias Dahm, Nicolás Porteiro
core   +3 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Assessment of side effects of venesection (phlebotomy) procedure in Iraqi patients presenting with erythrocytosis: single center experience

Iraqi Journal of Hematology, 2015
Background : Venesection or phlebotomy is generally considered to be a safe method, but occasionally adverse effects of varying severity may occur during or at the end of the procedure.
Eaman Marouf Muhammad, Raid Ahmed Alrubaye, Alaa Fadhil Alwan   +2 more
doaj  

Side-effects of generic.

Psychiatria Danubina, 2010
New trends in medicine which are much more oriented towards pharmacoeconomy, are ever so common these days. There's an aim within the focus of the health system which is cutting down treatment expenses, and that relates to psychiatry practice too. Prescription drugs issued by specialist doctors are allowed to be switched with cheaper ones of the same ...
Ružić, Klementina, Medved, Paola, Dadić-Hero, Elizabeta, Graovac, Mirjana, Tatalović-Vorkapić, Sanja, Rončević Gržeta, Ika   +5 more
openaire   +3 more sources

The Harmful Side Effects of Drug Prohibition [PDF]

, 2009
Some drugs make people feel good. That is why some people use them. Some of these drugs are alleged to have side effects so destructive that many advise against their use. The same may be said about statutes that attempt to prohibit the manufacture, sale,
Barnett, Randy E
core   +1 more source