Results 201 to 210 of about 2,166,400 (310)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Author Correction: Effects of electroconvulsive therapy on hippocampal longitudinal axis and its association with cognitive side effects. [PDF]

Commun Med (Lond)
Ousdal OT, Argyelan M, Laroy M, Anand A, Bouckaert F, Camprodon JA, Cano M, Cardoner N, Dannlowski U, Dols A, Emsell L, Espinoza R, Hebbrecht K, Hurlemann R, Jorgensen M, Kiebs M, Kishimoto T, Narr KL, Nordanskog P, Opel N, Redlich R, Rhebergen D, Sartorius A, Schrijvers D, Sienaert P, Soriano-Mas C, Takamiya A, Ten Doesschate F, Tendolkar I, Urretavizcaya M, van Diermen L, van Eijndhoven P, van Wingen G, van Waarde J, Vandenbulcke M, Verdijk J, Wade BSC, Antoine Y, Brekke N, Prudic J, McClintock S, Kessler U, Bartsch H, Odegaard K, Haavik J, Hammar Å, Abbott C, Oltedal L.   +47 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Vaccine side effects after vaccination against COVID-19 in employees at an University Hospital in Austria. [PDF]

Sci Rep
Schwarz-Martelanz CM, Hoffmann M, Wedrich A, Berghold A, Reininghaus E, Reinisch S, Borenich A, Sendlhofer G.   +7 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Side Effect [PDF]

, 2020
openaire   +1 more source

Tumoricidal Activity and Side Effects of Radiolabeled Anti-NCAM [131I]-Iodine-ERIC1 in Neuroblastoma-Bearing Mice [PDF]

Thomas Fischer, Felix Dietlein, Detlev Bongartz, Martin Klehr, Beate Zimmermanns, Matthias Schmidt, Angela Mohr, Fabian Mohr, F. Sudbrock, Philipp Krapf, Alexander Drzezga, Markus Dietlein, Klaus Schomäcker   +12 more
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Side Effects of COVID-19 Vaccination Among Medical Students in Bangladesh: A Cross-Sectional Study. [PDF]

Cureus
Islam ASMS, Sanjana S, Azad SU, Saify S, Trisha MS, Nahid MH.   +5 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source