Results 91 to 100 of about 4,809,367 (307)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Zhongguo Jianchuan Yanjiu[Objectives] To study the effect of side-hull layouts of Trimaran Small Waterplane Area Center Hull(TriSWACH) with circular transverse section on residual resistance and compare its residual resistance with that of slender trimaran.[Methods] The CFD ...
Zhang Mingxia +2 more
doaj +1 more source
Advances in Civil Engineering, 2019 This paper presents the results from a full-scale field study on the 3 different types of cast-in-place piles: rotary drilling piles (RDPs), manual digging piles (MDPs), and impact drilling piles (IDPs), for a bridge construction project of Wuqi–Dingbian
Zhijun Zhou, Tao Yang, Haobo Fan
doaj +1 more source
South Island Dairy Event proceedings Smart SIDE
, 2003 A partnership involving Dexcel, Lincoln University, and South Island Dairy ...
SIDE
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Gay Side Story Scrapbook [PDF]
, 1983 Scrapbook containing photographs and ephemera from original 1983 production of Gay Side Story. The full playbill can be seen here.https://digitalcommons.usm.maine.edu/gay_side_story/1001/thumbnail ...
Gay Side Story Collection
core +1 more source
, 1960 Interview with Elsie Side, as part of the Hearing Hazelton History project, managed by the Hazelton Area Historical Association.Attribution ...
core
Antimicrobial drug use and resistance in Europe [PDF]
, 2008 Our study confronts the use of antimicrobial agents in ambulatory care with the resistance trends of 2 major pathogens, Streptococcus pneumoniae and Escherichia coli, in 21 European countries in 2000–2005 and explores whether the notion that ...
Grundmann, Hajo +8 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source