Results 271 to 280 of about 594,994 (354)

Distinct thalamic functional connectivity and volume patterns across focal epilepsies in children: A multimodal neuroimaging study

open access: yesEpilepsia, EarlyView.
Abstract Objective The thalamus is a key hub in seizure propagation, and its nuclei are emerging targets for neuromodulation. However, the contributions of individual nuclei to epileptic networks remain unclear, particularly in children, who are less studied than adults.
Xiyu Feng   +11 more
wiley   +1 more source

Amygdala enlargement associated with remote epileptogenic lesions

open access: yesEpilepsia, EarlyView.
Abstract Objective To determine the prevalence and possible causes of amygdala enlargement in patients with drug‐resistant temporal lobe epilepsy. Methods Patients were retrospectively identified via a radiology information system and a large language model.
Horst Urbach   +5 more
wiley   +1 more source

Multimodal approach to characterize surgically removed epileptogenic zone from patients with focal drug‐resistant epilepsy: From operating room to wet lab

open access: yesEpilepsia Open, EarlyView.
Abstract Objective We have established a comprehensive sample handling protocol designed for the multiscale assessment of epileptogenic tissue. This protocol aims to identify novel therapeutic targets and enhance the diagnosis and stratification of patients with drug‐resistant epilepsy, thereby optimizing their treatment with anti‐seizure medications ...
Jenni Kyyriäinen   +24 more
wiley   +1 more source

Stretched Radial Trajectory Design for Efficient MRI with Enhanced K-Space Coverage and Image Resolution. [PDF]

open access: yesBioengineering (Basel)
Gong LS   +8 more
europepmc   +1 more source

Late‐onset unexplained epilepsy as a risk factor for cognitive impairment and dementia: Protocol for a multi‐center prospective longitudinal observational study (ELUCID)

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Late‐onset unexplained epilepsy (LoUE), defined as epilepsy onset after age 55 without an obvious cause, is an important risk factor for dementia. Studies have shown that 10%–25% of individuals with LoUE develop dementia within 3–4 years following their first seizure.
Alice D. Lam   +13 more
wiley   +1 more source

Whole brain volume loss is associated with a short-term disability progression in relapse-activity free multiple sclerosis. [PDF]

open access: yesJ Neurol
Opfer R   +18 more
europepmc   +1 more source

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