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Integrity of Storage Media for Clinical Applications with SIFT-MS Instruments
2006Tedlar™ bags are a promising medium for remote breath collection and later analysis using SIFT-MS for disease diagnosis. It is important to understand the changes in integrity of samples stored in Tedlar™ bags. However, there is little work into this problem completed to date, and thus little known about these issues.
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Assessing SIFT-MS Method Feasibility (Procedure 1)
The marked difference in the analytical approach of SIFT-MS compared with the conventional GC and LC techniques means that the feasibility of method transfer – or new method development – for SIFT-MS should be evaluated prior to experimental work. Drawing on principles discussed in Part 1 of this book, this chapter describes a procedure by which the ...openaire +1 more source
Modifying an Existing SIFT-MS Method (Procedure 7)
SIFT-MS, with its chromatography-free, soft chemical ionisation approach to the analysis of volatile compounds requires different procedures for modifying validated test methods compared to GC. This chapter provides procedures for modifying SIFT-MS methods involving addition or removal of analytes, modification to product ion selections, a change of ...openaire +1 more source
Breath Collection Equipment for Clinical Applications with SIFT-MS Instruments
2006Real time detection of Volatile Organic Compounds (VOCs) using Selected Ion Flow Tube – Mass Spectrometry (SIFT-MS) provides a unique opportunity for research into breath testing for clinical diagnosis. However, before engaging in research into breath analytes as markers of disease, appropriate breath collection methods are required.
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Preparing the Automated SIFT-MS Instrument for Analysis (Procedure 2)
Selected ion flow tube mass spectrometry (SIFT-MS) instruments have different operational procedures compared to conventional chromatographic instruments, since they are based on different principles. This chapter describes, in a general manner, how to prepare a SIFT-MS instrument for analysis, together with a coupled robotic autosampler. Additionally,openaire +1 more source
Validating SIFT-MS Analysis of Volatiles in Breath
Current Analytical Chemistry, 2013Malina Storer +3 more
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Measuring VOCs in Christchurch ambient air : using SIFT-MS technique
2002The project is aimed at monitoring the volatile organic compounds (VOCs) that may be regarded as undesirable in Christchurch's ambient air. Nine VOCs viz NH3 (ammonia), C2H4 (acetylene), C3H6OH (methanol), C2H5OH (ethanol), CH3CHO (acetaldehyde), C6H6 (benzene), C7H8 (toluene) and C8H10 (xylene) were-selected to be examined diurnally and seasonally ...
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Application of SIFT-MS in Monitoring Volatile Compounds in Fruits and Vegetables
Current Analytical Chemistry, 2013Nutsuda Sumonsiri, Sheryl Barringer
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Advances in On-line Absolute Trace Gas Analysis by SIFT-MS
Current Analytical Chemistry, 2013Patrik Spanel, David Smith
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