Results 111 to 120 of about 1,815,787 (311)

Rivers as Creative Ecologies

open access: yesOpen Rivers
By Sigma Colón and Juli Clarkson. We explore how activists, artists, scholars, and rivers might co-create riverine engagements that interrupt the extractive capitalist, heteropatriarchal, and watershed-colonialist projects that have degraded rivers and ...
Sigma Colón and Juli Clarkson
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Bacterial Flagellin-Specific Chaperone FliS Interacts with Anti-Sigma Factor FlgM [PDF]

open access: bronze, 2014
Anna V. Galeva   +5 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

$\sigma$-Relations, $\sigma$-functions and $\sigma$-antifunctions

open access: yes, 2009
In this article we develop the concepts of $\sigma$-relation and $\sigma$-function, following the same steps as in Set Theory. First we define the concept of ordered pair and then we build the Cartesian Product of $\sigma$-sets so that we can define the concepts of $\sigma$-relation and $\sigma$-function.
openaire   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

PENGARUH PEMAHAMAN KURIKULUM, KEPEMIMPINAN KEPALA SEKOLAH, SARANA DAN PRASARANA TERHADAP KINERJA GURU

open access: yesEconomic Education Analysis Journal, 2019
Tujuan dari penelitian ini adalah untuk mendeskripsikan dan menganalisis pengaruh pemahaman kurikulum, kepemimpinan kepala sekolah, sarana dan prasarana terhadap kinerja guru di MTs N Pamotan Kabupaten Rembang.
Sigma Adha Astianto, Ade Rustiana
doaj  

Modified Sigma Filter For Processing Images Corrupted By Multiplicative And Impulsive Noise

open access: green, 1996
Vladimir Lukin   +3 more
openalex   +1 more source

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