Results 121 to 130 of about 1,815,787 (311)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
B.R.S. renormalisation of some on-shell closed algebras of symmetry transformations : N=2 and 4 supersymmetric non-linear sigma models [PDF]
, 1994 Guy Bonneau
openalex +1 more source
Low‐clock‐speed time‐interleaved architecture for a polar delta–sigma modulator transmitter
, 2022 Nasser Erfani Majd, Rezvan Fani
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FEBS Open Bio, EarlyView.Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
Study of the release kinetics of dalbavancin from bone allografts
Journal of Materials Science: Materials in MedicineBone infections are common and difficult to treat, and secondary bone defects, which are often observed, may require a bone allograft. In this case, the surgeon will add antibiotics (usually vancomycin) in direct contact with the bone graft during the ...
Roger Erivan +6 more
doaj +1 more source
, 2016 We determine the convolution sums Sigma(l+27m= n) sigma(l)sigma(m) and Sigma(l+32m= n) sigma(l)sigma(m) for all positive integers n. We then use these evaluations together with known evaluations of other convolution sums to determine the numbers of representations of n by the octonary quadratic forms x(1)(2) + x(1)x(2) + x(2)(2) + x(3)(3) + x(3)x(4 ...
Alaca, Saban, Kesicioglu, Yavuz
openaire +1 more source