Results 141 to 150 of about 1,815,787 (311)

Longitudinal <i>in vivo</i> (<i>R</i>)-[¹⁸F]FBFP PET imaging for preclinical evaluation of cerebral sigma-1 receptor after ischemic stroke. [PDF]

Theranostics
Yang J, Liu L, Zhou H, Huang C, Wang D, Wang Z, Shi Y, Song S, Deng X, Zhu Y, Zhao J, Tang Z, Jia H, Zhu X.   +13 more
europepmc   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Structural insights into σ28-dependent transcription initiation and its regulation by anti-sigma factor in Pseudomonas aeruginosa. [PDF]

Nucleic Acids Res
Sheenu, Kumar V, Sahoo PK, Kandiah E, Jain D.   +4 more
europepmc   +1 more source

Sick Sigmas [PDF]

Journal of Oncology Practice, 2009
openaire   +2 more sources

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Determination of canine ROTEM Sigma reference ranges and comparative analysis with ROTEM Delta. [PDF]

Front Vet Sci
Jourdan A, Noval Montero J, Troussier G, Anderco A, Dania C, Moumadah Y, Cambournac M.   +6 more
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

PINK1/Parkin promotes liver regeneration via Sigma-1 ubiquitination to inhibit ER-Mitochondrial calcium transfer. [PDF]

Theranostics
Xu J, Wang Y, Zhong W, Hu H, Zhang Y, Gao Y, Wang P, Rao Z, Zhou H, Wang X.   +9 more
europepmc   +1 more source

Penerapan Metode Six Sigma Untuk Mengurangi Jumlah Defect Pada Proses Cetak Majalah Di Percetakan UD. Ajib Jaya

, 2022
Umar Sahid, Anggia Kalista, Novi Hendra Wirawan, Susanti Dhini Anggraini   +3 more
openalex   +2 more sources

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source