Results 11 to 20 of about 770,157 (273)
Common myths of six sigma demystified [PDF]
Purpose – Six Sigma has been part of our business lexicon for more than a decade. Debates on its emergence as a strategic initiative have created critics who consider it as an old wine in a new bottle. Is Six Sigma a management fad? This article presents
Kumar, Maneesh +4 more
core +4 more sources
We have discovered and synthesized a series of indole-based derivatives as novel sigma-2 (σ 2) receptor ligands. Two ligands with high σ 2 receptor affinity and subtype selectivity were then radiolabeled with F-18 in good radiochemical yields and purities, and evaluated in rodents.
Ying Zhang +9 more
openaire +3 more sources
(125I)iodoazidococaine, a photoaffinity label for the haloperidol-sensitive sigma receptor. [PDF]
A carrier-free radioiodinated cocaine photo-affinity label, (-)-3-(125I)iodo-4-azidococaine [(125I)IACoc], has been synthesized and used as a probe for cocaine-binding proteins. Photoaffinity labeling with 0.5 nM (125I)IACoc resulted in selective derivatization of a 26-kDa polypeptide with the pharmacology of a sigma receptor in membranes derived from ...
J R, Kahoun, A E, Ruoho
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An application of Six Sigma to reduce waste [PDF]
Six Sigma has been considered a powerful business strategy that employs a well-structured continuous improvement methodology to reduce process variability and drive out waste within the business processes using effective application of statistical tools ...
Antony, Jiju
core +4 more sources
Distance Magic Cartesian Products of Graphs
A distance magic labeling of a graph G = (V,E) with |V | = n is a bijection ℓ : V → {1, . . . , n} such that the weight of every vertex v, computed as the sum of the labels on the vertices in the open neighborhood of v, is a constant.
Cichacz Sylwia +3 more
doaj +1 more source
Novel ligands with the 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline or 5,6-dimethoxyisoindoline pharmacophore were designed and synthesized for evaluation of their structure-activity relationship to the sigma-2 (σ2) receptor and developed as suitable PET radioligands.
Tao Wang +10 more
openaire +3 more sources
Group-antimagic Labelings of Multi-cyclic Graphs
Let $A$ be a non-trivial abelian group. A connected simple graph $G = (V, E)$ is $A$-\textbf{antimagic} if there exists an edge labeling $f: E(G) \to A \backslash \{0\}$ such that the induced vertex labeling $f^+: V(G) \to A$, defined by $f^+(v) = \Sigma$
Dan Roberts, Richard Low
doaj +1 more source
Calcium Mobilisation Assay in Response to Chemokine Stimulation
This assay is used to measure calcium mobilization in lymphocytes (either in primary cells or cell lines) in response to chemokine stimulation using ratiometric analysis. It has also been used for measuring TCR mediated calcium flux.
Darran Cronshaw
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Studying the salt dependence of the binding of sigma70 and sigma32 to core RNA polymerase using luminescence resonance energy transfer. [PDF]
The study of protein-protein interactions is becoming increasingly important for understanding the regulation of many cellular processes. The ability to quantify the strength with which two binding partners interact is desirable but the accurate ...
Bryan T Glaser +4 more
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Union of Distance Magic Graphs
A distance magic labeling of a graph G = (V,E) with |V | = n is a bijection ℓ from V to the set {1, . . . , n} such that the weight w(x) = ∑y∈NG(x) ℓ(y) of every vertex x ∈ V is equal to the same element μ, called the magic constant.
Cichacz Sylwia, Nikodem Mateusz
doaj +1 more source

