Results 121 to 130 of about 2,302,822 (346)

On Globalized Traces for the Poisson Sigma Model. [PDF]

Commun Math Phys, 2022
Moshayedi N.
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Investigating the quality of hemovigilance process using the first two steps of Six Sigma model: a cross-sectional study. [PDF]

BMC Health Serv Res, 2023
Molaahmadi-Hassanabadi F, Mehrolhassani MH, Rahimisadegh R.   +2 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Implementing the six sigma model on the treatment of congenital hypothyroidism: An analytical hierarchy process. [PDF]

Med J Islam Repub Iran, 2021
Ebrahimipour H, Shojaei S, Esfandyari A, Karimi SE, Vafaee Najar A, Esmaily H.   +5 more
europepmc   +1 more source

The Variational Problem and Background Field in the Renormalization Group Method for Nonlinear Sigma Models [PDF]

, 2023
Abhishek Goswami
openalex   +1 more source

Topological sigma models [PDF]

Communications in Mathematical Physics, 1988
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Moduli spaces of instantons in flag manifold sigma models. Vortices in quiver gauge theories

Journal of High Energy Physics
In this paper, we discuss lumps (sigma model instantons) in flag manifold sigma models. In particular, we focus on the moduli space of BPS lumps in general Kähler flag manifold sigma models. Such a Kähler flag manifold, which takes the form U n 1 + ⋯ + n
Toshiaki Fujimori, Muneto Nitta, Keisuke Ohashi   +2 more
doaj   +1 more source

A Solution to the Polonyi Problem in the Minimum SUSY-GUT

, 1994
We show that the Polonyi problem is solved in the minimum SUSY-GUT model in which a self-coupling strength for a heavy Higgs $\Sigma$, $\lambda\Sigma^{3}$, is very small $\lambda\sim 10^{-6}$. It is stressed that with this small $\lambda$ the mass of the
Moroi, T., Yanagida, T.
core   +2 more sources