Results 241 to 250 of about 23,658,748 (362)
FEBS Open Bio, EarlyView.Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel +4 more
wiley +1 more source
Flexural Behavior of Bidirectionally Graded Lattice
Advanced Engineering Materials, EarlyView., 2023 An experimental study of the bending behavior of bidirectional body‐centered cubic lattice beams is conducted in comparison to uniform and unidirectional counterparts of electron beam melted SS 316 L. Experimental results are used to develop and validate a finite element model which is subsequently used to conduct parametric studies to assess the ...
Chamini Rodrigo +4 more
wiley +1 more source
Scaling contributions to the free energy in the 1/n expansion of O(n) nonlinear sigma models in d-dimensions [PDF]
, 1998 M. Dilaver, Paolo Rossi, Y. Gündüç
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FEBS Open Bio, EarlyView.Measuring AMP‐activated protein kinase (AMPK) activity in vitro is crucial for testing AMPK activators or inhibitors with therapeutic potential. Here, we report an enzyme‐linked immunosorbent assay (ELISA)‐based AMPK activity assay with simple steps and high sensitivity, which offers a simple, robust, and cost‐effective alternative to traditional ...
Trezze P. Nguyen, Shangze Lyu, Yang Liu
wiley +1 more source
A Variational Beam Model for Failure of Cellular and Truss‐Based Architected Materials
Advanced Engineering Materials, EarlyView., 2023 Herein, a versatile and efficient beam modeling framework is developed to predict the nonlinear response and failure of cellular, truss‐based, and woven architected materials. It enables the exploration of their design space and the optimization of their mechanical behavior in the nonlinear regime. A variational formulation of a beam model is presented
Konstantinos Karapiperis +3 more
wiley +1 more source
Construction of supercharges for the one-dimensional supersymmetric nonlinear sigma model [PDF]
, 1999 Alan Macfarlane, A.J. Mountain
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FEBS Open Bio, EarlyView.SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang +9 more
wiley +1 more source
Architected Lattices with a Topological Transition
Advanced Engineering Materials, EarlyView., 2023 This article develops topological metamaterials showing multidirectional two‐step deformation under compression by embedding contact‐enabled topological mechanisms into lattice structures. Experiments on 3D‐printed 2D and 3D lattices and finite element simulations are conducted to demonstrate the working principle of the topological metamaterials.
Shivam Agarwal, Lihua Jin
wiley +1 more source