Results 201 to 210 of about 7,711,295 (297)

Recapitulating gestational progression: a high-throughput 3D bioprinted vascularized human placenta demonstrating stage-specific molecular and functional signatures of human pregnancy. [PDF]

Sci Rep
Antich C, Chen YC, Noel J, Qu Y, Fang Y, Frebert S, Tao D, Richardson LS, Menon R, Song MJ, Ferrer M.   +10 more
europepmc   +1 more source

2d Sigma Models and Geometry

Supersymmetric nonlinear sigma models have target spaces that carry interesting geometry. The geometry is richer the more supersymmetries the model has. The study of models with two dimensional world sheets is particularly rewarding since they allow for torsionful geometries. In this review I describe and exemplify the relation of $2d$ supersymmetry to
openaire   +2 more sources

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Thalamic transcranial electrical stimulation with temporal interference enhances sleep spindle activity during a daytime nap. [PDF]

Sleep Adv
Bruno S, Mat B, Schaeffer EL, Haber I, Fan Z, Prahl SP, Wilcox MR, Strainis EP, Loring MD, Alauddin T, Smith RF, Achermann P, Beerli S, Capstick M, Neufeld E, Kuster N, Marshall W, Albantakis L, Jones SG, Cirelli C, Boly M, Tononi G.   +21 more
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

SIGMA: self-supervised inference of gene networks via masked auto-encoding. [PDF]

Front Genet
Wang Q, Zhang Z, Liao NQ, Yang S, He Z.
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

<i>N</i>-propargylputrescine as a minimal-tag probe for imaging putrescine dynamics in cellular homeostasis and stress. [PDF]

iScience
Owczarek A, Duchnowska A, Sas Z, Zakrzewski M, Florkowska A, Nalepa M, Skweres A, Suchożebski F, Mąka A, Szymanowski J, Michaluk P, Winiarska K, Cieśla M, Marusiak A, Serwa RA, Węgrzynowicz M.   +15 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Development and Psychometric Testing of an Instrument to Measure Servant Leadership Behaviors in Magnet Nurse Leaders. [PDF]

Worldviews Evid Based Nurs
Hall H, O'Malley P.
europepmc   +1 more source