Results 121 to 130 of about 14,038,334 (310)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Nonsmoothing in a single conservation law with memory
Electronic Journal of Differential Equations, 2001 It is shown that, provided the nonlinearity $sigma$ is strictly convex, a discontinuity in the initial value $u_0(x)$ of the solution of the equation $$ {partial over partial t} Big( u(t,x) + int_0^t k(t-s) (u(s,x)-u_0(x)),ds Big) + sigma(u)_x(t,x) = 0, $
G. Gripenberg
doaj
Cerâmica, 2006 We collected and analyzed literature data on ionic conductivity sigma and activation energy E A in the binary sodium silicate system in a wide composition range.
M. L. F. Nascimento +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Integrable deformations of T-dual $\sigma$ models
, 2016 Comment: 5 pages. References added. Projector reinstated in eq. (3).
Borsato, R, Wulff, L
openaire +3 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Optimal bilinear control for Gross-Pitaevskii equations with singular potentials
Electronic Journal of Differential Equations, 2019 We study the optimal bilinear control problem of the generalized Gross-Pitaevskii equation $$ i\partial_{t}u=-\Delta u+U(x)u+\phi(t)\frac{1}{|x|^{\alpha}}u +\lambda|u|^{2\sigma}u,\quad x\in \mathbb{R}^3, $$ where U(x) is the given external ...
Kai Wang, Dun Zhao
doaj
Química Nova, 2005 The Mössbauer analysis along with the structural Rietveld refinement based on powder X-ray data for the magnetic fraction (saturation magnetization, sigma = 19 J T-1 kg-1) separated from a tuffite material from Alto Paranaíba, state of Minas Gerais ...
Fernando Dias da Silva +4 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
On backward Kolmogorov equation related to CIR process
Modern Stochastics: Theory and Applications, 2018 We consider the existence of a classical smooth solution to the backward Kolmogorov equation \[ \left\{\begin{array}{l@{\hskip10.0pt}l}\partial _{t}u(t,x)=Au(t,x),\hspace{1em}& x\ge 0,\hspace{2.5pt}t\in [0,T],\\{} u(0,x)=f(x),\hspace{1em}& x\ge 0,\end ...
Vigirdas Mackevičius +1 more
doaj +1 more source