Results 181 to 190 of about 14,038,334 (310)

Characterizations of some classes of finite $\sigma$-soluble $P\sigma T$-groups

, 2017
Comment: 15 pages.
openaire   +1 more source

High Concentrations of β₂-Microglobulin Do Not Inhibit In Vitro Generation of Functional Dendritic Cells. [PDF]

J Immunol Res
Taborska P, Stakheev D, Krausova K, Bartunkova J, Smrz D.   +4 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Gut microbe-derived trimethylamine shapes circadian rhythms through the host receptor TAAR5. [PDF]

Elife
Mahen KK, Massey WJ, Orabi D, Brown AL, Jaramillo TC, Burrows A, Horak AJ, Dutta S, Mrdjen M, Mouannes N, Varadharajan V, Osborn LJ, Ye X, Yarbrough DM, Grubb T, Zajczenko N, Hohe R, Banerjee R, Linga P, Laungani D, Hajjar AM, Sangwan N, Dwidar M, Buffa JA, Swanson GR, Wang Z, Brown JM.   +26 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Humans optimally integrate cutaneous and proprioceptive cues in haptic size perception. [PDF]

Front Hum Neurosci
Allen KS, Goldreich D.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Multicenter application and evaluation of automated quality control systems on fully automated assembly lines. [PDF]

Pract Lab Med
Hou L, Li R, Xia L, Bai L, Yang S, Li P, Zhao Y, Chen G, Cheng S, Luo Y, Zhang X, Li Q, Liang Y, Niu W, Luo L, Han J, Ye X, Yi B, Zhang L, Zhang J, Zhang R, Shang X, Xiao M, Qiu L, Xu Y.   +24 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Fat's all, folks: culturing and manipulating peri-prostatic adipocytes to probe impacts on prostate cancer biology. [PDF]

J Endocrinol
Grunberg N, Winkler M, Hellawell G, Khoubehi B, Shah TT, Ahmed H, Bevan CL, Fletcher CE.   +7 more
europepmc   +1 more source