Results 201 to 210 of about 124,979 (266)

Large‐Scale Machine Learning to Screen for Small‐Molecule Senolytics

Advanced Intelligent Discovery, EarlyView.
A consistent workflow underpins all experiments in this study. A dedicated model‐selection dataset first identifies optimal hyperparameters for each algorithm. Models are then trained and rigorously evaluated on independent sets of molecules using the senolytic ratio SR. Comprehensive hyperparameter exploration across SMILES representations, task types,
Alexis Dougha, Jesus Gil, Pedro J. Ballester   +2 more
wiley   +1 more source

Acute Ileosigmoid Knotting in an Adult: CT Diagnosis of a Rapidly Progressive Closed-Loop Volvulus. [PDF]

Cureus
Bermejo ÍF, Qureshi PAAA, Ólason E, Einarsdóttir HM, Arkink E.   +4 more
europepmc   +1 more source

Spatially Informed Feature Selection and Machine Learning in Matrix‐Assisted Laser Desorption/Ionization Imaging for Cohort‐Scale Molecular Tissue Phenomics in Glioblastoma

Advanced Intelligent Discovery, EarlyView.
Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology.
Shad A. Mohammed, Denis Abu Sammour, Dirk C. Hoffmann, Philipp Sievers, Tobias Bausbacher, Melissa Hahn, Yasemin Ucal, Iris Mildenberger, Christiane A. Opitz, Stefan Schmidt, Michael Platten, Oliver Wasenmüller, Wolfgang Wick, Andreas von Deimling, Tobias Kessler, Carsten Hopf   +15 more
wiley   +1 more source

Inference of germinal center evolutionary dynamics via simulation-based deep learning. [PDF]

Elife
Ralph DK, Bakis AG, Galloway JG, Vora AA, Araki T, Victora GD, Song YS, DeWitt WS, Matsen FA.   +8 more
europepmc   +1 more source

Solving Data Overlapping Problem Using A Class‐Separable Extreme Learning Machine Auto‐Encoder

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The overlapping and imbalanced data in classification present key challenges. Class‐separable extreme learning machine auto‐encoding (CS‐ELM‐AE) is proposed, which is an enhancement of ELM‐AE that better handles overlapping data by clustering points from the same class together. Applying oversampling addresses imbalanced data.
Ekkarat Boonchieng, Wanchaloem Nadda
wiley   +1 more source

Sigmoid Volvulus Following Mechanical Bowel Preparation in an Elderly Patient. [PDF]

Cureus
Kim AJ, Reardon-Lochbaum R, Kalliath M.
europepmc   +1 more source

Robot‐Assisted Measurement of the Critical Micelle Concentration

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The study introduces (SIMO) smart integrator for manual operations, a robotic platform for precise, repeatable determination of (CMC) critical micelle concentration in surfactants. SIMO reduces standard deviation by 80% compared to manual methods. Surfactant, dye, and diluent selection, robotic protocols, and data handling are detailed.
Vincenzo Scamarcio, Gadi Slor, Josie Hughes, Francesco Stellacci   +3 more
wiley   +1 more source

Giant Sigmoid Fecaloma Causing Complete Large Bowel Obstruction in a Patient With Intellectual Disability: A Case Report. [PDF]

Cureus
Mora Moreno HE, Garcia Gonzalez N, Ramirez Gomez AY, Querea Vázquez J.   +3 more
europepmc   +1 more source

Predicting Performance of Hall Effect Ion Source Using Machine Learning

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This study introduces HallNN, a machine learning tool for predicting Hall effect ion source performance using a neural network ensemble trained on data generated from numerical simulations. HallNN provides faster and more accurate predictions than numerical methods and traditional scaling laws, making it valuable for designing and optimizing Hall ...
Jaehong Park, Guentae Doh, Dongho Lee, Youngho Kim, Changmin Shin, Su‐Jin Shin, Young‐Chul Ghim, Sanghoo Park, Wonho Choe   +8 more
wiley   +1 more source

A case of late-diagnosed colovesical fistula leading to complete colonic obstruction and urethral fecal diversion. [PDF]

J Med Case Rep
Hussen S, Mostafa K, Hassan M, Tofan S, Asaad W.   +4 more
europepmc   +1 more source