Results 31 to 40 of about 124,979 (266)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Colonic mucosal biopsy location can not affect the results of mucosal metabolomics and mucosal microbiota analysis in IBS

open access: yesFrontiers in Medicine, 2023
ObjectiveTo compare and analyze the mucosal metabolites and mucosal microbiota of different parts of colon in patients with IBS.MethodsA total of 10 patients with IBS-D and six healthy controls (HC) were enrolled.
Huiting Zhu   +6 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Sigmoid Volvulus: Diagnostic Modalities and Sigmoid Gangrene

open access: yesThe Eurasian Journal of Medicine, 2021
Cite this article as: Atamanalp SS, Disci E. Sigmoid Volvulus: Diagnostic Modalities and Sigmoid Gangrene. Eurasian J Med 2021; 53(2): 166-7.
Dişçi, Esra, Atamanalp, Sabri Selçuk
openaire   +4 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Path Planning Optimization of Smart Vehicle With Fast Converging Distance-Dependent PSO Algorithm

open access: yesIEEE Open Journal of Intelligent Transportation Systems
Path planning is a crucial technology and challenge in various fields, including robotics, autonomous systems, and intelligent transportation systems.
Muhammad Haris, Haewoon Nam
doaj   +1 more source

Sigmoidal inflation

open access: yesJournal of Physics Communications, 2020
Abstract In this paper we present a new cosmological inflationary model which is constructed using the Ivanov-Salopek-Bond method with a logistic generating function. We derive the inflationary observables as well as the duration and temperature of the subsequent reheating epoch of our model exactly, with no need to recur to the slow ...
E Díaz, O Meza-Aldama
openaire   +2 more sources

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

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