Results 151 to 160 of about 46,112 (265)

Knockdown of CREB3L4 Inhibits Autophagy and Reduces Cisplatin Resistance in Gastric Cancer Cells by Downregulating BAG3

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cisplatin resistance remains a major obstacle in the treatment of gastric cancer (GC), and autophagy has been increasingly recognized as a key cytoprotective mechanism contributing to chemoresistance. CREB3L4 is an endoplasmic reticulum membrane‐bound transcription factor that has been shown to regulate the expression of Bcl‐2 associated ...
Wen‐Ke Yin   +3 more
wiley   +1 more source

Sentio Bone‐Conduction Implant: Early Outcomes in Patients With Conductive or Mixed Hearing Loss

open access: yesThe Laryngoscope, EarlyView.
This study evaluated the initial clinical outcomes, safety, and audiological performance of the Sentio active bone‐conduction implant in patients with conductive or mixed hearing loss. Implantation resulted in significant improvements in hearing thresholds, speech recognition, speech perception in noise, and patient‐reported hearing benefit, with no ...
Katarzyna Beata Cywka   +4 more
wiley   +1 more source

Cerebral venous thrombosis and bilateral ophthalmoplegia complicating sphenoid sinusitis: a case report. [PDF]

open access: yesBMC Infect Dis
Ahmad R   +6 more
europepmc   +1 more source

MDSGene Systematic Review of Common Forms of Dominant Hereditary Spastic Paraplegia: Novel Insights

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Hereditary spastic paraplegia (HSP) is a neurodegenerative disorder characterized by progressive spasticity and lower limb weakness. The most common forms of autosomal dominant HSP are caused by pathogenic variants in SPAST (SPG4 or HSP‐SPAST), ATL1 (SPG3A or HSP‐ATL1), and REEP1 (SPG31 or HSP‐REEP1).
Ce Kang   +24 more
wiley   +1 more source

Relative aortic valve stiffness: a new parameter quantifying aortic stenosis. [PDF]

open access: yesAm J Physiol Heart Circ Physiol
Buffle E   +11 more
europepmc   +1 more source

The Application of Telemedicine in Surgery

open access: yesMed Research, EarlyView.
This figure provides an overview of the content presented in this article. Telemedicine is integrated throughout the entire surgical workflow, with distinct applications across the preoperative, intraoperative, and postoperative phases. These applications are enabled by a suite of supporting technologies, while the associated implementation challenges ...
Yufan Yang   +8 more
wiley   +1 more source

Extending the hyper‐logistic model to the random setting: New theoretical results with real‐world applications

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
We develop a full randomization of the classical hyper‐logistic growth model by obtaining closed‐form expressions for relevant quantities of interest, such as the first probability density function of its solution, the time until a given fixed population is reached, and the population at the inflection point.
Juan Carlos Cortés   +2 more
wiley   +1 more source

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