Results 231 to 240 of about 9,106,328 (402)

A flexible MRF approach to improve kinetic rate estimation with bSSFP-based hyperpolarized [1-¹³C]pyruvate MRI. [PDF]

Magn Reson Med
Bennett Haller A, Liu X, Sinha A, Sahin S, Larson PEZ, Wang CY.   +5 more
europepmc   +1 more source

Critical micellar concentration determination of pure phospholipids and lipid‐raft and their mixtures with cholesterol

Proteins: Structure, Function, and Bioinformatics, EarlyView.
Abstract Phospholipids in biological membranes establish a chemical equilibrium between free phospholipids in the aqueous phase (CMC) and self‐assembled phospholipids in vesicles, keeping the CMC constant. The CMC is different for each phospholipid, depends on the amount of cholesterol, and, according to the lipid‐chaperone hypothesis, controls the ...
Sofia Serravalle, Martina Pisano, Michele F. M. Sciacca, Nancy Salamone, Luciano Sicali, Giuseppe Mazzara, Luca Costa, Carmelo La Rosa   +7 more
wiley   +1 more source

Beyond the Usual Age: A Case Report on Segmental Colitis Associated With Diverticulitis in a Young Patient. [PDF]

Cureus
Brophy S, Hitomi N, Bains G.
europepmc   +1 more source

French multicentre prospective observational study of laparoscopicversusopen colectomy for sigmoid diverticular disease [PDF]

, 2005
A. Alvès, Yves Panís, K. Slim, Bruno Heyd, Fabrice Kwiatkowski, G. Mantion   +5 more
openalex   +1 more source

A model‐informed clinical trial simulation tool with a graphical user interface for Duchenne muscular dystrophy

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
Abstract Quantitative model‐based clinical trial simulation tools play a critical role in informing study designs through simulation before actual execution. These tools help drug developers explore various trial scenarios in silico to select a clinical trial design to detect therapeutic effects more efficiently, therefore reducing time, expense, and ...
Jongjin Kim, Juan Francisco Morales, Sanghoon Kang, Marian Klose, Rebecca J. Willcocks, Michael J. Daniels, Ramona Belfiore‐Oshan, Glenn A. Walter, William D. Rooney, Krista Vandenborne, Sarah Kim   +10 more
wiley   +1 more source

Examination of the frequency and localization of sigmoid canal with CBCT: A retrospective study. [PDF]

Medicine (Baltimore)
Kaya MS, Dogan ME, Kotanli S.
europepmc   +1 more source

Virtual Clinical Trial Reveals Significant Clinical Potential of Targeting Tumor‐Associated Macrophages and Microglia to Treat Glioblastoma

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Glioblastoma is the most aggressive primary brain tumor, with a median survival of 15 months with treatment. Standard‐of‐care (SOC) consists of resection, radio‐ and chemotherapy. Clinical trials involving PD‐1 inhibition with nivolumab combined with SOC failed to increase survival.
Blanche Mongeon, Morgan Craig
wiley   +1 more source

Modeling heterogeneity, commitment, and memory of bacterial spore germination. [PDF]

mBio
Li W, Mednick S, Setlow P, Li Y-Q.
europepmc   +1 more source

Letter 1: French multicentre prospective observational study of laparoscopic versus open colectomy for sigmoid diverticular disease (Br J Surg 2005; 92: 1520–1525) [PDF]

, 2006
Tarek Salem
openalex   +1 more source

Target‐Mediated Drug Disposition (TMDD) Revisited: High Versus Low‐Affinity Approximations of the TMDD Model

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Target‐mediated drug disposition (TMDD) is often associated with high‐affinity binding to a target resulting in nonlinear pharmacokinetics. For large molecules, such as monoclonal antibodies, this can lead to increased clearance at sub‐saturating concentrations.
Ronny Straube
wiley   +1 more source