Results 241 to 250 of about 9,106,328 (402)

Pterostilbene Exhibits Broad‐Spectrum Antiviral Activity by Targeting the Enterovirus Capsid, Inactivating Viral Particles, Blocking Viral Binding, and Protecting Mice From Lethal EV‐A71 Challenge

open access: yesPhytotherapy Research, EarlyView.
Pterostilbene (Pte) binds to the VP1 hydrophobic pocket of enteroviruses, stabilizing the viral capsid and preventing uncoating and RNA release. In vitro, Pte inactivates virions and impairs viral attachment, entry, and replication. In vivo, oral administration of Pte in hSCARB2‐transgenic mice reduces clinical symptoms and improves survival ...
Kuan‐Ting Chuang   +9 more
wiley   +1 more source

Formation of a β‐Endorphin Corona Mitigates Alzheimer's Amyloidogenesis

open access: yesSmall, EarlyView.
This study revealed the molecular mechanism of exercise‐induced β‐endorphin in suppressing the toxicity of Alzheimer's Aβ in vitro, in vivo and in silico. Abstract Senile plaques, comprised of nanosized aggregates of amyloid‐β (Aβ) peptides in the brain, are a pathological hallmark of Alzheimer's disease (AD).
Yunxiang Sun   +12 more
wiley   +1 more source

A proactive technique for reversal of Hartmann's procedure: lifting the rectal stump to the abdominal wall. [PDF]

open access: yesTech Coloproctol
Fukada A   +11 more
europepmc   +1 more source

Native Taylor/Non‐Taylor Dispersion–Mass Spectrometry (TNT‐MS) Allows Rapid Protein Desalting and Multiplexed, Label‐Free Ligand Screening

open access: yesSmall Methods, EarlyView.
Native mass spectrometry enables the label‐free study of noncovalent protein‐ligand complexes; however, it is incompatible with conventional molecular biology buffers. By exploiting the dependence of flow dynamics on the hydrodynamic radius, proteins are seperated, including protein‐ligand complexes, from non‐volatile salts and unbound small molecules ...
Jonathan Eisert   +10 more
wiley   +1 more source

Chronic Kidney Disease Increases Risk of Delayed Post‐Polypectomy Bleeding: A Large‐Scale Propensity Score‐Matched Analysis

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background The association between delayed post‐polypectomy bleeding and chronic kidney disease remains unclear. Objective This study investigated whether patients with chronic kidney disease are at an increased risk of delayed post‐polypectomy bleeding.
Hye Kyung Hyun   +12 more
wiley   +1 more source

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