Results 241 to 250 of about 72,494 (332)

A Case of Perforation of Sigmoid Colonal Diverticulum in Hemodialysis Patient due to Polycystic Kidney Disease

open access: bronze, 1998
Kazushi Nishizaki   +4 more
openalex   +2 more sources

Proteolytic stabilization of a spider venom peptide results in an orally active bioinsecticide

open access: yesPest Management Science, EarlyView.
Selective editing out of an insect gut protease cleavage site renders a spider‐derived insecticidal peptide active by ingestion by insect pests. Abstract BACKGROUND The toxin peptide U1‐AGTX‐Ta1b from the Hobo spider, Eratigena agrestis (Walckenaer, 1802), was studied to determine its potential to serve as a bioinsecticide.
Breck R. Davis   +12 more
wiley   +1 more source

CT colonography: revisited after 30 years. [PDF]

open access: yesInsights Imaging
Cadi M   +6 more
europepmc   +1 more source

Localization and quantity of Interstitial Cells of Cajal (ICC) in sigmoid colon among patients operated for diverticular disease of colon

open access: bronze, 2003
R. M. Herman   +5 more
openalex   +1 more source

A model‐informed clinical trial simulation tool with a graphical user interface for Duchenne muscular dystrophy

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
Abstract Quantitative model‐based clinical trial simulation tools play a critical role in informing study designs through simulation before actual execution. These tools help drug developers explore various trial scenarios in silico to select a clinical trial design to detect therapeutic effects more efficiently, therefore reducing time, expense, and ...
Jongjin Kim   +10 more
wiley   +1 more source

Concurrent Mpox and HSV-1 Proctitis in a Young Male With AIDS: A Case Report of Treatment Failure. [PDF]

open access: yesCase Rep Infect Dis
Sukhoroslov M   +5 more
europepmc   +1 more source

Prognostic Value of a Joint K‐PD Model With Tumor Size Dynamics and CA‐125 Kinetics in Recurrent Ovarian Cancer Patients: BOLD Phase II GINECO Study

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT In patients with recurrent advanced ovarian cancer, there is a need for companion tests to guide the development of innovative chemotherapy‐free treatments. The modeled longitudinal CA‐125 ELIMination rate constant K KELIM‐B was a major prognostic factor for progression‐free survival (PFS) and overall survival (OS) in recurrent advanced ...
Aurore Carrot   +13 more
wiley   +1 more source

USE OF THE RECTO‐SIGMOID INDEX (RSI) TO DIAGNOSE HIRSCHSPRUNG'S DISEASE (HD)

open access: bronze, 2005
R. Balongo García   +11 more
openalex   +1 more source

Semi‐Mechanistic Population Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling of Dupilumab on Pre‐Bronchodilator Forced Expiratory Volume in 1 Second (FEV1) in Uncontrolled Moderate‐To‐Severe Asthma

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT In this study, we investigated the pharmacokinetic/pharmacodynamic (PK/PD) relationship of dupilumab as an add‐on therapy in the intent‐to‐treat (ITT) uncontrolled moderate‐to‐severe asthma population and identified the factors significantly contributing to variability in forced expiratory volume in 1 second; (FEV1).
Li Zhang   +3 more
wiley   +1 more source

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