Results 271 to 280 of about 77,844 (314)

Outcome After Surgery for Colon Cancer in a National Cohort of Patients With and Without Inflammatory Bowel Disease

Alimentary Pharmacology &Therapeutics, EarlyView.
This national cohort study of patients surgically resected for colon cancer, during 2007–2021, compares survival outcomes of patients with and without inflammatory bowel diseases. The main results were that overall survival, recurrence‐free survival and cancer‐specific survival were lower in patients with IBD.
Erik Lundqvist, Karin Westberg, Sol Erika Boman, Ida H. Myrberg, Åsa H. Everhov, Pär Myrelid, Bengt Glimelius, Anna Martling, Caroline Nordenvall   +8 more
wiley   +1 more source

Right-sided descending colon with necrotizing enterocolitis: a rare case report. [PDF]

Front Pediatr
Wang T, Xia S, Liu M, Zhang Y, Liu Y.
europepmc   +1 more source

State‐dependent regulation of the Kv7.2 channel voltage sensor by QO‐58

British Journal of Pharmacology, EarlyView.
Background and Purpose KV7(KCNQ) potassium channels are key modulators of neuronal excitability, and promising targets for development of drugs for epilepsy and pain. We investigated a candidate KV7 drug, QO‐58, which has been previously described but has an unclear mechanism of action.
Richard Kanyo, Shawn M. Lamothe, Thomas M. Hammond, Harley T. Kurata   +3 more
wiley   +1 more source

Metastatic Patterns of Apical Lymph Node and Prognostic Analysis in Rectal and Sigmoid Colon Cancer-A Multicenter Retrospective Cohort Study of 2809 Cases. [PDF]

Cancers (Basel)
Zhang M, Zhao F, Wu A, Du X, Zhou L, Mei S, Wei F, Hu S, Liu X, Yang H, Xu L, Xiao Y, Wang X, Liu Q, On Behalf Of The Chinese Apical Lymph Node Study Consortium.   +14 more
europepmc   +1 more source

New biosensors and transgenic mice for multiplex cGMP imaging

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters, Martin Thunemann, Barbara Birk, Susanne Feil, Viacheslav O. Nikolaev, Moritz Lehners, Robert Feil   +6 more
wiley   +1 more source

Atypical bilateral papilledema during the puerperium: a case report. [PDF]

Front Med (Lausanne)
Jiang L, Jiang X, Li A, Liu M, Zhang Z, Tong Y.   +5 more
europepmc   +1 more source

RNA Analysis Uncovers Pathogenic PARN Variant in Dyskeratosis Congenita

Clinical Genetics, EarlyView.
Using WGS and RNA analysis, we identified a branch point‐disrupting variant in the PARN gene and elucidated its pathogenic molecular mechanism in a child with atypical dyskeratosis congenita presentation. ABSTRACT Dyskeratosis congenita (DC) is a rare genetic disorder caused by impaired telomere maintenance, leading to diverse clinical manifestations ...
Daria Akimova, Natalia Semenova, Tatiana Cherevatova, Mikhail Skoblov   +3 more
wiley   +1 more source

Experimental Disentangling of the Effects of Initial Population Size and Resource Availability on Weevil Population Dynamics

Entomologia Experimentalis et Applicata, EarlyView.
Initial population size and resource availability are key factors regulating population dynamics, with growth rates typically declining as populations increase but rising with greater resources. In maize weevils, however, we found an unexpected negative effect of resource availability on intrinsic growth rates, contrary to conventional expectations. We
Gessica Miranda Barros, Claudiane de Lima Braz, Joabe da Cruz Carvalho, Mateus Fonseca Barreto Cortes, Evandro dos Passos Gomes, Iara Alves Gomes, Andressa Milany Oliveira de Jesus, Abinailda Souza Lima, Pietra Rodrigues Oliveira Martins, Mateus Lemos do Nascimento, Adrianne Gabriela Cedro de Souza Novaes, Roberto Novaes, Raissa Castro Nunes, Andressa Andrade de Oliveira, Luisa Cravo de Oliveira, Vanessa Araujo de Oliveira, Laila Felix Santos Rocha, Thais Karine dos Santos Santana, Elidiane Santana Santos, Beatriz dos Santos Silva, Leidiane Marques da Silva, Mateus Ramos de Santana Trindade, Pamela Silva Veiga, Maria Fernanda Nascimento Velame, Guilherme de Oliveira   +24 more
wiley   +1 more source

When Bowel Preparation Worsens With Time: The Case of an Unknown Crohn's Fistula. [PDF]

ACG Case Rep J
Zoughlami A, Pedicelli A, Wyse JM.
europepmc   +1 more source

Massive lower gastrointestinal hemorrhage due to primary internal iliac arterial-sigmoid colon fistula. [PDF]

Acta Radiol Open
Li Q, Wang H, Chen Z, Ni Z.
europepmc   +1 more source