Results 71 to 80 of about 72,494 (332)

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

open access: yesAdvanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh   +3 more
wiley   +1 more source

100 Days of COVID-19 in India: Current and Future Trends

open access: yesJournal of Pure and Applied Microbiology, 2020
COVID-19 classified under emerging infectious diseases has spread across the world resulting in many casualties. India reported its first case on 30th January 2020 and has completed 100 days in this pandemic period.
Sheetal Gouda   +2 more
doaj   +1 more source

An Animal‐Free Patient‐Derived Tissue‐Mimetic Biochip Model of the Human Synovial Membrane for Human‐Relevant Osteoarthritis Research

open access: yesAdvanced Healthcare Materials, EarlyView.
Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs   +17 more
wiley   +1 more source

Community-level Monitoring of HIV Spread [PDF]

open access: yes, 2020
Health departments are using HIV data to monitor HIV growth in real time. The main purpose of this monitoring is to come up with policies for efficient allocation of medical resources.
Malekian, Sina
core  

Cold Atmospheric Plasma Selectively Disrupts Breast Cancer Growth in a Bioprinted 3D Tumor‐Stroma Co‐Culture Model

open access: yesAdvanced Healthcare Materials, EarlyView.
This research introduces a cold plasma‐based platform for treating breast cancer bone metastases. Using a novel bioprinted 3D tumor‐stroma model, it highlights the selective antitumor effects of plasma‐generated reactive species. The platform aims to advance non‐invasive therapeutic strategies, offering potential clinical applications in controlling ...
Laura M. Bouret   +4 more
wiley   +1 more source

Has Anyone Ever Died of Old Age? [PDF]

open access: yes, 2003
The omission of aging as a legal cause of death and the largely unrecognized contribution the aging process plays in mortality is ...
Harry R. Moody, Loeonard Hayflick
core  

Multienzyme (3‐in‐1)‐Mimicking a Single Nucleobase‐Derived Bionanozyme for Versatile Environmental and Biomedical Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reports the development of bioinspired 2D crystalline Bionanozyme derived from a single nucleobase. It effectively mimics multienzyme activity to detect and remove phenolic pollutants, identify disease biomarkers with high sensitivity, and protect cells from oxidative stress.
Subrat Vishwakarma   +8 more
wiley   +1 more source

Close association between abnormal expressed enzymes of energy metabolism and diarrhea-predominant irritable bowel syndrome

open access: yesChinese Medical Journal, 2019
. Background:. Irritable bowel syndrome (IBS) is one of the most common functional intestinal diseases, but its pathogenesis is still unknown. The present study aimed to screen the differentially expressed proteins in the mucosa of colon between IBS with
Chun-Yan Zhang   +4 more
doaj   +1 more source

Fourier Descriptor Pada Klasifikasi Daun Herbal Menggunakan Support Vector Machine Dan Naive Bayes

open access: yesJurnal Teknologi Informasi dan Ilmu Komputer, 2023
Daun herbal bermanfaat sebagai obat alternatif karena kandungan alaminya dapat menyembuhkan berbagai penyakit dan menjaga kesehatan tubuh. Klasifikasi citra daun herbal digunakan untuk membedakan jenis tanaman herbal berdasarkan bentuk daun.
Mutmainnah Samir   +3 more
doaj   +1 more source

Hirschsprung's Diseases Complicated by Sigmoid Volvulus: A Systematic Review

open access: yesBalkan Medical Journal, 2020
Hirschsprung's disease and sigmoid volvulus can sometimes be seen in the same patient.To investigate the presence of Hirschsprung's disease in patients with sigmoid volvulus and to discuss the diagnosis and treatment methods.Systematic review.This systematic review has been reported in line with the Preferred Reporting Items for Systematic Reviews and ...
Ufuk Uylas, Orgun Gunes, Cuneyt Kayaalp
openaire   +4 more sources

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