Results 81 to 90 of about 72,494 (332)

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

Advanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček   +8 more
wiley   +1 more source

Evaluation of the primary anastomosis side effects in patients with sigmoid volvulus in Imam Hossein and Firoozgar Hospitals in 2014-2015

Journal of Acute Disease, 2017
Objective: The term volvulus is derived from a Latin word volvere means to turn, twist which is mainly referred to as twisting of sigmoid and can lead to ischemia and gangrene. Nowadays, it is the 3rd most common reason of bowel obstruction mostly in the
Mahdi Alemrajabi, Mostafa Hosseini, Behzad Nemati Honar, Mahdi Kayyal, Adnan Tizmaghz, Amirmohsen Jalaeefar   +5 more
doaj   +1 more source

DeepCare: A Deep Dynamic Memory Model for Predictive Medicine

, 2016
Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies.
A Graves, AB Jensen, BB Granger, J Futoma, JM Corbin, JS Mathias, K Orphanou, PB Jensen, R Henriques, S Hochreiter, SJ Henly, T Tran, T Tran, Y LeCun   +13 more
core   +1 more source

Natural Design of a Stabilized Cross‐β Fold: Structure of the FuA FapC from Pseudomonas Sp. UK4 Reveals a Critical Role for Stacking of Imperfect Repeats

Advanced Materials, EarlyView.
We report a 3.2 Å cryoEM structure of functional amyloid protein FapC from Pseudomonas sp. UK4, an essential component of bacterial biofilm, which reveals a Greek key‐shaped protofilament, supports bioinformatically determined motifs, nuances AlphaFold predictions, emphasizes heterogeneous cross‐β stacking in amyloid cross‐seeding and shows strain ...
Yanting Jiang, Samuel Peña‐Díaz, Zhefei Zhang, Anders Ogechi Hostrup Daugberg, Marcos López Hernández, Janni Nielsen, Qiaojie Huang, Shenghan Qin, Morten K. D. Dueholm, Mingdong Dong, Jan Skov Pedersen, Qin Cao, Daniel E. Otzen, Huabing Wang   +13 more
wiley   +1 more source

Tailored for Real-World: A Whole Slide Image Classification System Validated on Uncurated Multi-Site Data Emulating the Prospective Pathology Workload. [PDF]

, 2020
Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin & eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher efficiency and ...
Ayyagari, Devi, Bonham, Michael J., Chamarthi, Ramachandra Vikas, Cockerell, Clay J., Feeser, Theresa A., Ianni, Julianna D., Lee, Jason B., Motaparthi, Kiran, Olsen, Thomas G., Sankarapandian, Sivaramakrishnan, Soans, Rajath E., Stavish, Coleman C.   +11 more
core   +1 more source

Development of a Sensitive Electrochemical Aptasensor for Non‐Small Cell Lung Cancer Extracellular Vesicle Detection

Advanced Materials Interfaces, EarlyView.
A novel electrochemical aptasensor enables the selective detection of lung cancer‐derived EVs by targeting the CD44 surface marker. The sensor uses a self‐assembled monolayer (SAM) for aptamer immobilization and achieves label‐free EV detection through electrochemical impedance spectroscopy.
Zarinah M. Amin, Volker Nock, Paula Brooksby, Renee V. Goreham   +3 more
wiley   +1 more source

Cerebral Venous Sinus Thrombosis and Posterior Reversible Encephalopathy Syndrome in a Preeclamptic Woman [PDF]

Journal of Clinical and Diagnostic Research, 2015
Cerebral venous sinus thrombosis (CVST) and posterior reversible encephalopathy syndrome (PRES) are two rare diseases which may present with similar symptoms and signs. We report a case with coexisting PRES and CVST in a preeclamptic woman.
Nadiye Köroglu, Sinem Sudolmus, Elif Asli Sarıoglu, Alpay Alkan, Ramazan Dansuk   +4 more
doaj   +1 more source

Review of Coherent Anti‐Stokes Raman Scattering Nonresonant Background Removal and Phase Retrieval Approaches: From Experimental Methods to Deep Learning Algorithms

Advanced Photonics Research, EarlyView.
Coherent anti‐stokes Raman spectroscopy (CARS) enables high‐resolution vibrational imaging, yet non‐resonant background (NRB) distorts spectral fidelity. This review highlights NRB removal methods—from experimental strategies and numerical algorithms to emerging deep learning techniques.
Rajendhar Junjuri, Thomas Bocklitz
wiley   +1 more source

Sigmoid Volvulus Due Chagas Disease

, 2020
American Trypanosomiasis, also known as Chagas disease, is a parasitic disease caused by Trypanosoma cruzi and transmitted by hematophagous vectors, occupies the fourth place as a cause of loss of potential years of life between infectious and parasitic diseases, and has an acute presentation form and chronic, in which it can present complications at ...
openaire   +4 more sources

Sigmoid-cervical fistula due to diverticular disease

Journal of Obstetrics and Gynaecology, 2010
Fistulae in the female genital tract are an infrequent but severe complication of diverticular disease (Hjern et al. 2007).
A. Kamel, J Eddy
openaire   +3 more sources