Results 141 to 150 of about 217,698 (308)

Computational Design and Glycoengineering of Interferon‐Lambda for Nasal Prophylaxis Against Respiratory Viruses

Advanced Science, EarlyView.
This study presents an engineered human interferon‐lambda (hIFN‐λ) as an intranasal prophylactic against respiratory viruses. By combining AI‐guided backbone redesign and glycoengineering, the authors developed a thermostable, protease‐resistant, and scalable variant with improved mucosal penetration.
Jeongwon Yun, Seungju Yang, Jae Hyuk Kwon, Luiz Felipe Vecchietti, Ji Hyun Choi, Mi‐ra Choi, Keun Bon Ku, Hyun‐Joo Ro, Kyun‐Do Kim, Meeyoung Cha, Hyun Jung Chung, Ji Eun Oh, Ho Min Kim   +12 more
wiley   +1 more source

Sigmoid functions in reliability based management

Periodica Polytechnica Social and Management Sciences, 2007
This paper introduces the theoretical background of a few possible applications of the so-called sigmoid-type functions in manufacturing and service management. An extended concept of reliability, derived from fuzzy theory, is discussed here to illustrate how reliability based management decisions can be made consistent, when handling of weakly defined
openaire   +2 more sources

High‐Asymmetry Metasurface: A New Solution for Terahertz Resonance via Active Learning‐Augmented Diffusion Model

Advanced Science, EarlyView.
A prior knowledge‐guided diffusion model augmented by physics‐constrained active learning is developed to design high‐asymmetry terahertz metamaterials. Trained on only a small set of classical structures, the model efficiently generates new high‐metrics designs.
Qiqi Dai, Yinpeng Wang, Cheng Xu, Dongxiao Li, Prakash Pitchappa, Thomas Caiwei Tan, Ranjan Singh, Chengkuo Lee   +7 more
wiley   +1 more source

Research on Nonlinear Dynamic Characteristics of Fractional Order Resonant DC-DC Converter Based on Sigmoid Function

Fractal and Fractional
Resonant DC-DC converters are a class of strongly nonlinear systems with rich nonlinear phenomena. In order to describe the dynamic behavior of resonant DC-DC converters more accurately, the nonlinear dynamic behavior of fractional order (FO) resonant DC-
Lingling Xie, Guangwei Xu
doaj   +1 more source

[Effects of ulnar styloid and sigmoid notch fractures on postoperative wrist function of patients with distal radius fracture].

, 2020
P Zhang, Bo Jia, X K Chen, Y Wang, Wengang Huang, Renfa Lai, Z W Wang, Jin Xiong, Tikang Wang   +8 more
openalex   +2 more sources

Single‐Field Evolution Rule Governs the Dynamics of Representational Drift in Mouse Hippocampal Dorsal CA1 Region

Advanced Science, EarlyView.
Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen, Shuyang Yao, Sihui Cheng, Jiayi Tian, Ang Li, Yusen Yan, Xiang Zhang, Yuanjing Liu, Yumeng Wang, Qichen Cao, Chenglin Miao   +10 more
wiley   +1 more source

Predicting MammaPrint Recurrence Risk from Breast Cancer Pathological Images Using a Weakly Supervised Transformer

Advanced Science, EarlyView.
This study presents CPMP, a weakly supervised transformer model that predicts MammaPrint recurrence risk directly from routine histopathological images of early‐stage HR+/HER2− breast cancer patients. CPMP enables spatial heatmap visualization, analysis of cellular‐level interaction patterns, and an in‐depth characterization of morphological phenotypes
Chaoyang Yan, Linwei Li, Xiaolong Qian, Yang Ou, Zhidong Huang, Zhihan Ruan, Wenting Xiang, Hong Liu, Jian Liu   +8 more
wiley   +1 more source

Needle‐free, Liquid Metal‐embedded Electrospray Deposition System for Controlled Microdroplet Printing

Advanced Science, EarlyView.
The liquid metal‐embedded electrospray deposition (LM‐ESD) system combines stable droplet spray, clog‐free and recoverable operation, and simplified fabrication in a single polydimethylsiloxane (PDMS) microfluidic platform. By eliminating external electrodes, it offers needle‐free, robust, and scalable droplet array printing, ensuring reproducibility ...
Chaeyeong Kang, Seokbeom Roh, Hyunjun Park, Sugeun Lee, Taeha Lee, Sang Won Lee, Hansung Kim, Jinsung Park, Gyudo Lee, Insu Park   +9 more
wiley   +1 more source

Heavy Prussian Blue Analog with Magnetic Ordering above 400 K

Advanced Science, EarlyView.
A cyanido‐bridged vanadium(II)–hexacyanomolybdate(III) Prussian Blue analog synthesized mechanochemically exhibits ferrimagnetic ordering above 400 K. SQUID magnetometry and XMCD experiments confirm antiparallel alignment of V and Mo moments. This establishes hexacyanomolybdate(III) as a robust precursor for high‐temperature molecule‐based magnets ...
Michał Magott, Gabriela Handzlik, Dominik Dzierżek, Alexey Maximenko, Itziar Oyarzabal, Nathan J. Yutronkie, Fabrice Wilhelm, Andrei Rogalev, Dawid Pinkowicz   +8 more
wiley   +1 more source

Short- and long-term outcomes as well as anal function of transanal natural orifice specimen extraction surgery versus conventional laparoscopic surgery for sigmoid colon or rectal cancer resection: a retrospective study with over 5-year follow-up. [PDF]

, 2022
Jianlu Zhang, Weiqing Li, Ying Li, Buhe Amin, Nengwei Zhang, Zhipeng Sun, Bin Zhu   +6 more
openalex   +1 more source