Results 161 to 170 of about 217,698 (308)

Leveraging 3D Molecular Spatial Visual Information and Multi‐Perspective Representations for Drug Discovery

open access: yesAdvanced Science, EarlyView.
A deep learning framework called MolVisGNN is proposed to fuse 3D molecular visual information of drugs with multi‐source features, which proves the importance of 3D molecular visual information of drugs and the advancedness of this model in the field of drug discovery, and provides a reference for how to more comprehensively express small molecule ...
Zimai Zhang   +9 more
wiley   +1 more source

MLP Based Tan-Sigmoid Activation Function for Cardiac Activity Monitoring [PDF]

open access: diamond, 2019
Hashim Fakroul Ridzuan   +4 more
openalex   +1 more source

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

open access: yesAdvanced Science, EarlyView.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin   +4 more
wiley   +1 more source

A Biologically Informed Vision‐Guided Framework for Interpretable T Cell Receptor–Epitope Binding Prediction

open access: yesAdvanced Science, EarlyView.
Integrating hierarchical physicochemical features via a bio‐inspired design, the DAISY framework robustly predicts T‐cell receptor binding, significantly outperforming state‐of‐the‐art models on unseen epitopes. It uniquely offers visual interpretability via Score‐CAM visualizations and profound clinical relevance, correlating with T‐cell expansion ...
Yajing Yuan   +9 more
wiley   +1 more source

Supramolecular Phase Change Materials for Spatiotemporally Thermal Energy Utilization

open access: yesAdvanced Science, EarlyView.
The long‐term storage as well as switchable and controllable release of thermal energy using activated perethylated pillar[5]arene EtP5 (EtP5α) is demonstrated for the first time. High thermal energy storage capacity can be maintained over 20 thermal cycles and for more than 365 days at room temperature, which is the PCMs that can store thermal energy ...
Miaomiao Yan   +5 more
wiley   +1 more source

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