Results 41 to 50 of about 220,793 (302)

SAI, a Sensible Artificial Intelligence that plays Go

, 2019
We propose a multiple-komi modification of the AlphaGo Zero/Leela Zero paradigm. The winrate as a function of the komi is modeled with a two-parameters sigmoid function, so that the neural network must predict just one more variable to assess the winrate
Amato, Gianluca, Gini, Rosa, Metta, Carlo, Morandin, Francesco, Parton, Maurizio, Pascutto, Gian-Carlo   +5 more
core   +1 more source

DANTE: Deep AlterNations for Training nEural networks

, 2020
We present DANTE, a novel method for training neural networks using the alternating minimization principle. DANTE provides an alternate perspective to traditional gradient-based backpropagation techniques commonly used to train deep networks. It utilizes
Balasubramanian, Vineeth N, Chavali, Surya Teja, Kar, Purushottam, Kudugunta, Sneha, Sankar, Adepu Ravi, Sinha, Vaibhav B   +5 more
core   +1 more source

Enzyme-Based Logic: OR Gate with Double-Sigmoid Filter Response

, 2012
The first realization of a biomolecular OR gate function with double-sigmoid response (sigmoid in both inputs) is reported. Two chemical inputs activate the enzymatic gate processes resulting in the output signal: chromogen oxidation, which occurs when ...
Bocharova, Vera, Katz, Evgeny, Privman, Vladimir, Zavalov, Oleksandr   +3 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Modularity of Biochemical Filtering for Inducing Sigmoid Response in Both Inputs in an Enzymatic AND Gate

, 2013
We report the first systematic study of designed two-input biochemical systems as information processing gates with favorable noise-transmission properties accomplished by modifying the gate's response from convex shape to sigmoid in both inputs. This is
Bakshi, Saira, Halamek, Jan, Katz, Evgeny, Privman, Vladimir, Zavalov, Oleksandr   +4 more
core   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Some properties of the Blumberg's hyper-log-logistic curve

Biomath, 2018
The paper considers the sigmoid function definedthrough the hyper-log-logistic model introduced by Blumberg. We study the Hausdorff distance of this sigmoid to the Heaviside function, which characterises the shape of switching from 0 to 1.
Roumen Anguelov, Nikolay Kyurkchiev, Svetoslav Markov   +2 more
doaj   +1 more source

An improved neuroendocrine–proportional–integral–derivative controller with sigmoid-based secretion rate for nonlinear multi-input–multi-output crane systems

Journal of Low Frequency Noise, Vibration and Active Control, 2020
This paper proposes an improved neuroendocrine–proportional–integral–derivative controller for nonlinear multi-input–multi-output crane systems using a sigmoid-based secretion rate of the hormone regulation.
Mohd Riduwan Ghazali, Mohd Ashraf Ahmad, Raja Mohd Taufika Raja Ismail, M Osman Tokhi   +3 more
doaj   +1 more source

Assessing sigmoidal function on memristive maps

Heliyon
Los memristores ofrecen un elemento crucial para la construcción de mapas discretos que han atraído una atención significativa en dinámicas complejas y diversas aplicaciones potenciales. En este estudio, hemos integrado la función memristiva y sigmoidal para proponer técnicas de mapeo innovadoras.
Vo Phu Thoai, Viet–Thanh Pham, Giuseppe Grassi, Shaher Momani   +3 more
openaire   +4 more sources

Dynamic Precipitation during High‐Pressure Torsion of a Magnesium–Manganese Alloy

Advanced Engineering Materials, EarlyView.
An ultrafine‐grained alloy is produced by high‐pressure torsion of solutionized Mg–1.35 wt% Mn. Precipitation of nanometer‐scale Mn particles during deformation provides pinning sites. This prevents the formation of a bimodal grain structure and results in a finer grain size than for pure Mg.
Julian M. Rosalie, Anton Hohenwarter
wiley   +1 more source