Results 51 to 60 of about 217,698 (308)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Some properties of the Blumberg's hyper-log-logistic curve

open access: yesBiomath, 2018
The paper considers the sigmoid function definedthrough the hyper-log-logistic model introduced by Blumberg. We study the Hausdorff distance of this sigmoid to the Heaviside function, which characterises the shape of switching from 0 to 1.
Roumen Anguelov   +2 more
doaj   +1 more source

Dynamic Smoothing, Filtering and Differentiation of Signals Defining the Path of the UAV

open access: yesSensors, 2022
On the example of a control system for an unmanned aerial vehicle, we consider the problems of filtering, smoothing and restoring derivatives of reference action signals.
Aleksey S. Antipov   +3 more
doaj   +1 more source

APPROXIMATION OF THE CUT FUNCTION BY STANNARD AND RICHARD SIGMOID FUNCTIONS [PDF]

open access: hybridInternational Journal of Pure and Apllied Mathematics, 2016
Several sigmoidal functions (Stannard [10], [16], [19], [23], Richards [13], [17], [20], [22], Chapman–Richards [5]) find numerous applications in various fields related to life sciences, chemistry, physics, artificial intelligence, population dynamics, plant biology, fuzzy set theory, etc.
Антон Илиев   +2 more
openalex   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

On the Approximation of the Cut and Step Functions by Logistic and Gompertz Functions

open access: yesBiomath, 2015
We study the uniform approximation of the sigmoid cut function by smooth sigmoid functions such as the logistic and the Gompertz functions. The limiting case of the interval-valued   step function is   discussed  using   Hausdorff metric.
Anton Iliev Iliev   +2 more
doaj   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

Contrast Enhancement Using Sensitivity Model-Based Sigmoid Function

open access: yesIEEE Access, 2019
For indirect contrast enhancement, researchers have proposed various transformation functions based on histogram equalization and gamma correction.
Seung Park, Yong-Goo Shin, Sung-Jea Ko
doaj   +1 more source

Discontinuities in recurrent neural networks [PDF]

open access: yes, 1997
This paper studies the computational power of various discontinuous real computational models that are based on the classical analog recurrent neural network (ARNN).
Gavaldà Mestre, Ricard   +1 more
core   +1 more source

Experimental Analysis and Physics‐Based Analytical Model on Twisted and Coiled Artificial Muscles

open access: yesAdvanced Engineering Materials, EarlyView.
Twisted and coiled artificial muscles made from silver‐coated nylon fibers are investigated through experiments and analytical modeling. The actuators achieve contractions up to 19.3% and specific work of 8 kJ kg−1, though efficiency remains limited (≈0.15%) by thermal losses.
Salvatore Garofalo   +3 more
wiley   +1 more source

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