Results 71 to 80 of about 11,244,578 (287)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Assistive translation technology for deaf people: translating into and animating Irish sign language [PDF]

open access: yes, 2008
Machine Translation (MT) for sign languages (SLs) can facilitate communication between Deaf and hearing people by translating information into the native and preferred language of the individuals.
Morrissey, Sara
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Dicta-Sign - Use of a Multilingual Corpus to Improve Sign Language Technology

open access: yes, 2010
International audienceDicta-Sign is a three-year EU-funded research project which started in January 2009. It aims to improve online communication for Deaf people by promoting the development of sign language based web applications.
Worseck, Satu   +12 more
core   +3 more sources

Secondary analysis of hand-offs in internal medicine using the I-PASS mnemonic

open access: yesBMC Medical Education
Background Miscommunications account for up to 80% of preventable medical errors. Mnemonics like I-PASS (Illness severity, Patient summary, Actions list, Situation awareness, Synthesis) have demonstrated a positive impact on reducing error rates ...
Aurélie Huber   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Collaborating With Physicians to Redesign a Sign-Out Tool [PDF]

open access: yesErgonomics in Design: The Quarterly of Human Factors Applications, 2009
Physician sign-out is a mechanism for transferring patient information from one group of hospital care-givers to another at shift changes. Support tools are critical to the success of sign-out. To ensure that a tool is effective, designers must collaborate with end users, but collaboration can be difficult when working with users who are busy and have ...
Justin M. Devoge   +4 more
openaire   +1 more source

The Interpreters' Newsletter 19, Sign Language Interpreting

open access: yes, 2014
This issue of The Interpreters’ Newsletter aims to address a number of topics of interest in this growing area of Interpreting Studies presented in the form of discussion on prevailing situations, personal impressions on the profession (e.g.
Schaumberger Elke, Freelance Sign Language interpreter   +12 more
core  

The relationship between deaf and hard of hearing students' Japanese Sign Language and Japanese Language Proficiency [PDF]

open access: yes, 2009
The present study represents an attempt to investigate the relationship between Japanese Sign Language proficiency and the Japanese literacy skills of high school students who are deaf or hard or hearing (D/HH). A Pilot Test of Japanese Sign Language was
Fordyce, Mariela
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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