Results 61 to 70 of about 250,256 (245)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Target Localization by Resolving the Time Synchronization Problem in Bistatic Radar Systems Using Space Fast-Time Adaptive Processor

EURASIP Journal on Advances in Signal Processing, 2009
The proposed technique allows the radar receiver to accurately estimate the range of a large number of targets using a transmitter of opportunity as long as the location of the transmitter is known.
D. Madurasinghe, A. P. Shaw
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Using an Activity Based on Constructivism To Help Students Develop a More Integrated Understanding of Cell Signaling Pathways

Journal of Microbiology & Biology Education, 2019
In subjects like cell biology, genetics, and immunology, a solid understanding of signal transduction is key to mastering new content.  Often times students’ approach to learning signal transduction pathways relies heavily on memorization.  In this paper,
Laura MacDonald, Verónica A. Segarra, Amanda Solem   +2 more
doaj   +1 more source

Performance Limits for Signals of Opportunity-Based Navigation

ION GNSS+, The International Technical Meeting of the Satellite Division of The Institute of Navigation
Submitted to ION GNSS+
Zanirato, Francesco, Ardizzon, Francesco, Crosara, Laura, Curzio, Alessio, Canzian, Luca, Tomasin, Stefano, Laurenti, Nicola   +6 more
openaire   +3 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Overview of the system-level anti-jamming capability and developmental challenges of low-earth-orbit signal-of-opportunity

Frontiers in Physics
Signal-of-Opportunity (SOP) navigation based on Low-Earth-Orbit (LEO) satellite constellations has increasingly become a research hotspot. Due to the large number of LEO satellites, wide spectrum coverage, and strong signal power, LEO satellite Signal-of-
Lihao Yao, Lihao Yao, Bin Fan, Honglei Qin, Deyong Xian, Mengli Wang, Boyun Gu, Sumin Chen, Sumin Chen, Changhong Wang, Changhong Wang, Xuyu Wang, Jiemin Shen, Dongfang Jiang, Heng Wei, Haoyuan Yu, Bingjie Liu, Shuai Shao   +17 more
doaj   +1 more source

Signal Transduction in the Footsteps of Goethe and Schiller

Cell Communication and Signaling, 2009
The historical town of Weimar in Thuringia, the "green heart of Germany" was the sphere of Goethe and Schiller, the two most famous representatives of German literature's classic era.
Feller Stephan M, Ehrhardt Christina, Giehl Klaudia, Kieser Arnd, Thiel Gerald, Serfling Edgar, Entschladen Frank, Lindquist Jonathan A, Friedrich Karlheinz, Ullrich Oliver, Schaper Fred, Janssen Ottmar, Hass Ralf   +12 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Remote Sensing using Signals of Opportunity

, 2013
Today, there are more than eight thousand satellites in space. Therefore, Radio Frequency (RF) signals broadcast from satellites can be accessed from almost every point on the earth. There will be number of satellites available at most points on earth with different frequency bands.
Yertay, Alibek, Garrison, James L
openaire   +1 more source