Results 81 to 90 of about 2,300,983 (302)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Optimisation of the bone single photon emission computed tomography in oncology patients

Journal of Health Sciences
Introduction: The introduction of hybrid imaging systems such as Single Photon Emission Computed Tomography/Computed Tomography (SPECT/CT) has completely changed the scanning procedure of conventional diagnostic nuclear medicine protocols.
Nusret Salkica, Amela Begić, Adnan Beganović, Fuad Julardžija, Adnan Šehić, Halil Ćorović, Safet Hadžimusić, Amra Skopljak-Beganović   +7 more
doaj   +1 more source

Low Frequency Noise Characterization and Signal-to-Noise Ratio Optimization for Silicon Hall Cross Sensors

IEEE Journal of the Electron Devices Society, 2015
In this paper, silicon-based Hall cross sensors with different device dimensions and carrier densities are designed and fabricated. Low frequency noise behavior regarding to the device dimension and carrier density of the Hall cross sensors has been ...
Dongli Zhang, Mingxiang Wang, Kai Sun
doaj   +1 more source

Unbiased Injection of Signal-Dependent Noise in Variance-Stabilized Range [PDF]

, 2016
<p>The design, optimization, and validation of many image processing or image-based analysis systems often requires testing of the system performance over a dataset of images corrupted by noise at different signal-to-noise ratio regimes.
Vieira, Marcelo, Borges, Lucas, Foi, Alessandro   +2 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Material imaging study of 3D printing materials for diagnostic radiology phantom development

Brazilian Journal of Radiation Sciences
The 3D printing techniques have found applications across diverse fields, significantly enhancing design and manufacturing processes. The impact of this growth is particularly notable in radiology, where 3D printing has been applied to developing quality
Marcus Oliveira, Matheus Savi, Adriano Vitor, Daniel Villani, Marco Andrade, Carlos Ubeda, Mauricio Mitsuo Monção   +6 more
doaj   +1 more source

Chinese Syllable and Phoneme Identification in Noise and Reverberation

Archives of Acoustics, 2014
Chinese is a tonal language, which differentiates it from non-tonal languages in the Western countries. A Chinese character consists of an initial, a final, and a tone. In the present study, the effects of noise and reverberation on the Chinese syllable,
Jianxin PENG
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

3D MR neurography with gadolinium contrast to improve the visualization of pelvic nerves and the branches

Frontiers in Physiology
ObjectiveTo evaluate the effectiveness of 3D NerveVIEW sequence with gadolinium contrast on the visualization of pelvic nerves and their branches compared to that without contrast.MethodsParticipants were scanned twice using 3D NerveVIEW sequence with ...
Hui Liu, Zhibo Xiao, Li Tao, Mingmei Tang, Yong Xu, Yuanrui Pan, Ke Zhang, Xueke Qiu, Fajin Lv, Fajin Lv   +9 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source