Results 141 to 150 of about 4,892,908 (297)
Biased Pressure: Cyclic Reinforcement Learning Model for Intelligent Traffic Signal Control. [PDF]
Sensors (Basel), 2022 Ibrokhimov B, Kim YJ, Kang S.
europepmc +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Deep Q-network-based traffic signal control models. [PDF]
PLoS One, 2021 Park S, Han E, Park S, Jeong H, Yun I.
europepmc +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Charged Ferroelectric Domain Walls for Deterministic ac Signal Control at the Nanoscale. [PDF]
Nano Lett, 2021 Schultheiß J +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Quantifying the impact of non-stationarity in reinforcement learning-based traffic signal control. [PDF]
PeerJ Comput Sci, 2021 Alegre LN, Bazzan ALC, da Silva BC.
europepmc +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Real-Time Adaptive Traffic Signal Control in a Connected and Automated Vehicle Environment: Optimisation of Signal Planning with Reinforcement Learning under Vehicle Speed Guidance. [PDF]
Sensors (Basel), 2022 Maadi S +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source