Results 221 to 230 of about 3,092,636 (291)

Disproportionality analysis of drug-associated progressive multifocal leukoencephalopathy using spontaneous reports: A 20-year signal detection study based on the FAERS database. [PDF]

PLoS One
Wang H, Li X, Shangguan L.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Signal Processing Method and Evaluation Method for Weak Doppler Signal Detection. [PDF]

Sensors (Basel)
Xi C, Zhou J, Nie X, Jin S.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Performance of the Self-Controlled Case Series With Active Comparators for Drug Safety Signal Detection Using the French Administrative Healthcare Database (SNDS). [PDF]

Pharmacoepidemiol Drug Saf
Coste A, Wong AYS, Haguinet F, Bate A, Douglas IJ.   +4 more
europepmc   +1 more source

Signal stratification of antineoplastic drugs associated with interstitial lung disease: A multi-method signal detection analysis using the FAERS database. [PDF]

Medicine (Baltimore)
Gong Z, Wang Q, Huang Y, Xu H.
europepmc   +1 more source

Age-stratified pharmacovigilance of azithromycin: a multimethod signal detection analysis in the FAERS database. [PDF]

J Pharm Policy Pract
Zhang Z, Li J, Zheng J, Liang Y, Ma L, Su L.   +5 more
europepmc   +1 more source

Determinants of Physicians' Referrals for Suspected Cancer Given a Risk-Prediction Algorithm: Linking Signal Detection and Fuzzy Trace Theory. [PDF]

Med Decis Making
Kostopoulou O, Pálfi B, Arora K, Reyna V.   +3 more
europepmc   +1 more source

Signal detection for pediatric patient deterioration with nursing students: An explanatory sequential design mixed-methods study. [PDF]

Int J Nurs Stud Adv
Zimpelman LT.
europepmc   +1 more source