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Detection algorithms and attentive points of safety signal using spontaneous reporting systems as a clinical data source

Briefings Bioinform., 2021
Continuous evaluation of drug safety is needed following approval to determine adverse events (AEs) in patient populations with diverse backgrounds.
Y. Noguchi, T. Tachi, H. Teramachi
semanticscholar   +1 more source

Signal Detection

Drug Safety, 2007
A primary aim in pharmacovigilance is the timely detection of either new adverse drug reactions (ADRs) or a relevant change of the frequency of ADRs that are already known to be associated with the drugs involved, i.e. signal detection. Adequate signal detection solely based on the human intellect (case-by-case analysis or qualitative signal detection)
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Signal Detection and Chlorpromazine

Human Factors: The Journal of the Human Factors and Ergonomics Society, 1971
Nine normal subjects were tested on an auditory signal detection task under six signal-to-noise conditions while under the influence of different dosages of chlorpromazine, a commonly used major tranquilizer. A significant subject-x-drug-dosage-level interaction was found, some subjects showing impairment of signal detection performance while on ...
M, Rappaport, H K, Hopkins
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Visual signal detection II Signal-location identification

Journal of the Optical Society of America A, 1984
We have measured the effect of signal-location uncertainty on the detectability of simple visual signals in uncorrelated image noise. An M-alternative forced-choice signal-location identification technique was used with values of M ranging from 2 to 1800.
A E, Burgess, H, Ghandeharian
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Monitoring Readily Detected Auditory Signals and Detection of Obscure Visual Signals

Perceptual and Motor Skills, 1963
Twenty-four Ss were required to detect infrequently and randomly occurring visual and auditory signals under six different schedules. In four of the sessions there were 40 visual signals and, respectively, 0, 20, 40, or 80 auditory signals. In two sessions there were 20 visual signals and 20 or 60 auditory signals.
J R, BINFORD, M, LOEB
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WiMax signal detection

MILCOM 2008 - 2008 IEEE Military Communications Conference, 2008
In this paper, we consider the detection of WiMax signals under noise uncertainty. Based on the special feature - cyclic prefix embedded in WiMax signals, we propose an optimal Neyman-Pearson likelihood test for the signal detection. We have derived rigorously the probability distribution function of the corresponding decision statistics under ...
Zhongding Lei, Francois Chin
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Detection of the Number of Signals by Signal Subspace Matching

IEEE Transactions on Signal Processing, 2021
We present a novel and computationally simple solution to the problem of detecting the number of signals, which is applicable to both white and colored noise, and to a very small number of samples.
M. Wax, A. Adler
semanticscholar   +1 more source

Signal Detection

2013
This volume is based on the 10th annual Harvard Symposium for the Quantitative Analysis of Behavior. The first Harvard Symposium was devoted to signal-detection analyses of reinforcement and choice behavior. The present volume reprises the original signal- detection theme, incorporating additional insights based on experimental and theoretical analyses
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Detection of rotating gravity signals

Biological Cybernetics, 1992
It is shown in the preceding paper that neurons with two-dimensional spatio-temporal properties to linear acceleration behave like one-dimensional rate sensors: they encode the component of angular velocity (associated with a rotating linear acceleration vector) that is normal to their response plane.
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Signal Detection Theory

2012
Signal detection theory (SDT), developed in the 1950s, is a framework of statistical methods used to model how observers classify sensory events [72, 169]. In this chapter we describe commonly used signal detection models and methods for fitting them. A recurring theme in this book is the use of the generalized linear model (GLM) to fit psychophysical ...
Kenneth Knoblauch, Laurence T. Maloney
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